PDB entry 5oia
View 5oia on RCSB PDB site
Description: Dissociation of biochemical and antiretroviral activities of Integrase-LEDGF Allosteric Inhibitors revealed by resistance of A125 polymorphic HIV-1
Class: viral protein
Keywords: HIV-1, Integrase, Catalytic core domain, VIRAL PROTEIN
Deposited on
2017-07-18, released
2018-03-07
The last revision prior to the SCOPe 2.07 freeze date was dated
2018-03-14, with a file datestamp of
2018-03-09.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: pol protein
Species: Human immunodeficiency virus 1 [TaxId:11676]
Gene: pol
Database cross-references and differences (RAF-indexed):
- Uniprot I0BY59
- conflict (93)
- conflict (154)
- conflict (175)
Domains in SCOPe 2.07: d5oiaa_ - Heterogens: MG, 9VK, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5oiaA (A:)
mgsshhhhhhssglvprgsmhgqvdcspgiwqldcthlegkvilvavhvasgyieaevip
aetgqetayfllklagrwpvktvhtdngsnftsaavkaacwwagikqefgipynpqsqgv
vesmnkelkkiigqvrdqaehlktavqmavfihnkkrkggiggysagerivdiiatdiqt
ke
Sequence, based on observed residues (ATOM records): (download)
>5oiaA (A:)
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsaavkaacwwagikqmnkelkkiigqvrdqaehlktavqmavfihnkkrkysag
erivdiiatdi