PDB entry 5niu

View 5niu on RCSB PDB site
Description: Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor
Class: immune system
Keywords: PD-L1, PD-1, immune checkpoint, immune system
Deposited on 2017-03-27, released 2017-12-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-12-06, with a file datestamp of 2017-12-01.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Programmed cell death 1 ligand 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NZQ7 (0-116)
      • expression tag (117-125)
    Domains in SCOPe 2.07: d5niua1, d5niua2
  • Chain 'B':
    Compound: Programmed cell death 1 ligand 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NZQ7 (0-116)
      • expression tag (117-124)
    Domains in SCOPe 2.07: d5niub1, d5niub2
  • Chain 'C':
    Compound: Programmed cell death 1 ligand 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NZQ7 (0-116)
      • expression tag (117-125)
    Domains in SCOPe 2.07: d5niuc1, d5niuc2
  • Chain 'D':
    Compound: Programmed cell death 1 ligand 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NZQ7 (0-116)
      • expression tag (117-126)
    Domains in SCOPe 2.07: d5niud1, d5niud2
  • Heterogens: 8YZ, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5niuA (A:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlkvq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaa
lehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5niuA (A:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlkvq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaa
lehhhh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5niuB (B:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlkvq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaa
lehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5niuB (B:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlkvq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaa
lehhh

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5niuC (C:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlkvq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaa
lehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5niuC (C:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlkvq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaa
lehhhh

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5niuD (D:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlkvq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaa
lehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5niuD (D:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlkvq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaa
lehhhhh