PDB entry 5lpl

View 5lpl on RCSB PDB site
Description: Crystal structure of the bromodomain of human CREBBP bound to the inhibitor XDM3c
Class: transcription
Keywords: bromodomain, protein-inhibitor complex, epigenetics, transcription
Deposited on 2016-08-13, released 2017-08-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: creb-binding protein
    Species: Homo sapiens [TaxId:9606]
    Gene: CREBBP, CBP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q92793 (2-118)
      • expression tag (0-1)
    Domains in SCOPe 2.07: d5lpla1, d5lpla2
  • Heterogens: 71X, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5lplA (A:)
    smrkkifkpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivknpmdlsti
    krkldtgqyqepwqyvddvwlmfnnawlynrktsrvykfcsklaevfeqeidpvmqslg