PDB entry 5dyt

View 5dyt on RCSB PDB site
Description: Crystal structure of human butyrylcholinesterase in complex with N-((1-benzylpiperidin-3-yl)methyl)-N-methylnaphthalene-2-sulfonamide
Class: hydrolase
Keywords: human butyrylcholinesterase, AD, alzheimer disease, sulfonamide, hydrolase
Deposited on 2015-09-25, released 2016-10-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-01-18, with a file datestamp of 2017-01-13.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cholinesterase
    Species: Homo sapiens [TaxId:9606]
    Gene: BCHE, CHE1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5dyta_
  • Chain 'B':
    Compound: cholinesterase
    Species: Homo sapiens [TaxId:9606]
    Gene: BCHE, CHE1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5dytb_
  • Heterogens: NAG, FUC, 5HB, GOL, EDO, UNX, FUL, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5dytA (A:)
teddiiiatkngkvrgmnltvfggtvtaflgipyaqpplgrlrfkkpqsltkwsdiwnat
kyansccqnidqsfpgfhgsemwnpntdlsedclylnvwipapkpknatvliwiygggfq
tgtsslhvydgkflarvervivvsmnyrvgalgflalpgnpeapgnmglfdqqlalqwvq
kniaafggnpksvtlfgesagaasvslhllspgshslftrailqsgsfnapwavtslyea
rnrtlnlakltgcsreneteiikclrnkdpqeillneafvvpygtplsvnfgptvdgdfl
tdmpdillelgqfkktqilvgvnkdegtaflvygapgfskdnnsiitrkefqeglkiffp
gvsefgkesilfhytdwvddqrpenyrealgdvvgdynficpaleftkkfsewgnnaffy
yfehrssklpwpewmgvmhgyeiefvfglplerrdnytkaeeilsrsivkrwanfakygn
pnetqnnstswpvfksteqkyltlntestrimtklraqqcrfwtsffpkv

    Sequence, based on observed residues (ATOM records): (download) 
    >5dytA (A:)
diiiatkngkvrgmnltvfggtvtaflgipyaqpplgrlrfkkpqsltkwsdiwnatkya
nsccqnidqsfpgfhgsemwnpntdlsedclylnvwipapkpknatvliwiygggfqtgt
sslhvydgkflarvervivvsmnyrvgalgflalpgnpeapgnmglfdqqlalqwvqkni
aafggnpksvtlfgesagaasvslhllspgshslftrailqsgsfnapwavtslyearnr
tlnlakltgcsreneteiikclrnkdpqeillneafvvpygtplsvnfgptvdgdfltdm
pdillelgqfkktqilvgvnkdegtaflvygapgfskdnnsiitrkefqeglkiffpgvs
efgkesilfhytdwvddqrpenyrealgdvvgdynficpaleftkkfsewgnnaffyyfe
hrssklpwpewmgvmhgyeiefvfglplerrdnytkaeeilsrsivkrwanfakygnpne
tqnnstswpvfksteqkyltlntestrimtklraqqcrfwtsffpkv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5dytB (B:)
teddiiiatkngkvrgmnltvfggtvtaflgipyaqpplgrlrfkkpqsltkwsdiwnat
kyansccqnidqsfpgfhgsemwnpntdlsedclylnvwipapkpknatvliwiygggfq
tgtsslhvydgkflarvervivvsmnyrvgalgflalpgnpeapgnmglfdqqlalqwvq
kniaafggnpksvtlfgesagaasvslhllspgshslftrailqsgsfnapwavtslyea
rnrtlnlakltgcsreneteiikclrnkdpqeillneafvvpygtplsvnfgptvdgdfl
tdmpdillelgqfkktqilvgvnkdegtaflvygapgfskdnnsiitrkefqeglkiffp
gvsefgkesilfhytdwvddqrpenyrealgdvvgdynficpaleftkkfsewgnnaffy
yfehrssklpwpewmgvmhgyeiefvfglplerrdnytkaeeilsrsivkrwanfakygn
pnetqnnstswpvfksteqkyltlntestrimtklraqqcrfwtsffpkv

    Sequence, based on observed residues (ATOM records): (download) 
    >5dytB (B:)
iiiatkngkvrgmnltvfggtvtaflgipyaqpplgrlrfkkpqsltkwsdiwnatkyan
sccqnidqsfpgfhgsemwnpntdlsedclylnvwipapkpknatvliwiygggfqtgts
slhvydgkflarvervivvsmnyrvgalgflalpgnpeapgnmglfdqqlalqwvqknia
afggnpksvtlfgesagaasvslhllspgshslftrailqsgsfnapwavtslyearnrt
lnlakltgcsreneteiikclrnkdpqeillneafvvpygtplsvnfgptvdgdfltdmp
dillelgqfkktqilvgvnkdegtaflvygapgfskdnnsiitrkefqeglkiffpgvse
fgkesilfhytdwvddqrpenyrealgdvvgdynficpaleftkkfsewgnnaffyyfeh
rssklpwpewmgvmhgyeiefvfglplerrdnytkaeeilsrsivkrwanfakygnpnet
nnstswpvfksteqkyltlntestrimtklraqqcrfwtsffpkv