PDB entry 5bwm

View 5bwm on RCSB PDB site
Description: The complex structure of C3cer exoenzyme and GDP bound RhoA (NADH-bound state)
Class: SIGNALING PROTEIN/Transferase
Keywords: ADP Ribose Transferases, Bacterial Toxins, SIGNALING PROTEIN-Transferase complex
Deposited on 2015-06-08, released 2015-06-24
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-08-19, with a file datestamp of 2015-08-14.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: transforming protein rhoa
    Species: Homo sapiens [TaxId:9606]
    Gene: RHOA, ARH12, ARHA, RHO12
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61586 (Start-178)
      • engineered mutation (24)
    Domains in SCOPe 2.07: d5bwma_
  • Chain 'B':
    Compound: ADP-ribosyltransferase
    Species: Bacillus cereus [TaxId:1396]
    Gene: c3cer
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5bwmb_
  • Heterogens: GDP, MG, NAI, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5bwmA (A:)
maairkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdt
agqedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkd
lrndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraal

    Sequence, based on observed residues (ATOM records): (download) 
    >5bwmA (A:)
airkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdtag
qedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlr
ndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraal

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5bwmB (B:)
gniptkpkdcnnvdkyklctnkeeadawgkkqfnkwskeeksairdytknarpyneflrm
hagkldsdptmkkkiesldkalnrkeakvndnikvyrgddawifgkeydnsiikngkvdr
ekfkeiqkkfqgktttefgyistsilidagyaktrpvmtefkvgsgthgaymnsddltay
pgqyelllprntvykiekiyiaidnntqkeqikveatik

    Sequence, based on observed residues (ATOM records): (download) 
    >5bwmB (B:)
kyklctnkeeadawgkkqfnkwskeeksairdytknarpyneflrmhagkldsdptmkkk
iesldkalnrkeakvndnikvyrgddawifgkeydnsiikngkvdrekfkeiqkkfqgkt
ttefgyistsilidagyaktrpvmtefkvgsgthgaymnsddltaypgqyelllprntvy
kiekiyiaidnntqkeqikveatik