PDB entry 4zhf

View 4zhf on RCSB PDB site
Description: Siderocalin-mediated recognition and cellular uptake of actinides
Class: Metal Binding Protein/inhibitor
Keywords: Metal Binding Protein-inhibitor complex
Deposited on 2015-04-24, released 2015-08-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-09-02, with a file datestamp of 2015-08-28.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: LCN2, HNL, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188 (Start-179)
      • engineered mutation (88)
    Domains in SCOPe 2.07: d4zhfa_
  • Chain 'B':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: LCN2, HNL, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188
      • engineered mutation (88)
    Domains in SCOPe 2.07: d4zhfb_
  • Chain 'C':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: LCN2, HNL, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188
      • engineered mutation (88)
    Domains in SCOPe 2.07: d4zhfc_
  • Chain 'D':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: LCN2, HNL, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188 (Start-179)
      • engineered mutation (88)
    Domains in SCOPe 2.07: d4zhfd_
  • Chain 'E':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: LCN2, HNL, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188
      • engineered mutation (88)
    Domains in SCOPe 2.07: d4zhfe_
  • Chain 'F':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: LCN2, HNL, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188
      • engineered mutation (88)
    Domains in SCOPe 2.07: d4zhff_
  • Heterogens: ZCM, 4OL, SO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4zhfA (A:)
gsqdstsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyel
kedksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqh
amvffkkvsqnreyfkitlygrtkeltselkenfirfskslglpenhivfpvpidqcidg

    Sequence, based on observed residues (ATOM records): (download) 
    >4zhfA (A:)
dstsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyelked
ksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqhamv
ffkkvsqnreyfkitlygrtkeltselkenfirfskslglpenhivfpvpidqcidg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4zhfB (B:)
gsqdstsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyel
kedksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqh
amvffkkvsqnreyfkitlygrtkeltselkenfirfskslglpenhivfpvpidqcidg

    Sequence, based on observed residues (ATOM records): (download) 
    >4zhfB (B:)
stsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyelkedk
synvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqhamvf
fkkvsqnreyfkitlygrtkeltselkenfirfskslglpenhivfpvpidqcid

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4zhfC (C:)
gsqdstsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyel
kedksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqh
amvffkkvsqnreyfkitlygrtkeltselkenfirfskslglpenhivfpvpidqcidg

    Sequence, based on observed residues (ATOM records): (download) 
    >4zhfC (C:)
stsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyelkedk
synvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqhamvf
fkkvsqnreyfkitlygrtkeltselkenfirfskslglpenhivfpvpidqcid

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4zhfD (D:)
gsqdstsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyel
kedksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqh
amvffkkvsqnreyfkitlygrtkeltselkenfirfskslglpenhivfpvpidqcidg

    Sequence, based on observed residues (ATOM records): (download) 
    >4zhfD (D:)
dstsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyelked
ksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqhamv
ffkkvsqnreyfkitlygrtkeltselkenfirfskslglpenhivfpvpidqcidg

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4zhfE (E:)
gsqdstsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyel
kedksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqh
amvffkkvsqnreyfkitlygrtkeltselkenfirfskslglpenhivfpvpidqcidg

    Sequence, based on observed residues (ATOM records): (download) 
    >4zhfE (E:)
dstsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyelked
ksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqhamv
ffkkvsqnreyfkitlygrtkeltselkenfirfskslglpenhivfpvpidqcid

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4zhfF (F:)
gsqdstsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyel
kedksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqh
amvffkkvsqnreyfkitlygrtkeltselkenfirfskslglpenhivfpvpidqcidg

    Sequence, based on observed residues (ATOM records): (download) 
    >4zhfF (F:)
stsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyelkedk
synvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqhamvf
fkkvsqnreyfkitlygrtkeltselkenfirfskslglpenhivfpvpidqcid