PDB entry 4z19

View 4z19 on RCSB PDB site
Description: Crystal structure of beta-ketoacyl-ACP synthase III (FabH) from Yersinia pestis with acetylated active site cysteine
Class: transferase
Keywords: fabh, fatty acid biosynthesis, condensing enzyme, thiolase fold, acetylated, transferase
Deposited on 2015-03-27, released 2015-05-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-10-28, with a file datestamp of 2015-10-23.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase 3
    Species: Yersinia pestis [TaxId:632]
    Gene: fabH, YPO1597, y1756, YP_2257
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ZFT7 (0-315)
      • engineered mutation (228)
    Domains in SCOPe 2.07: d4z19a1, d4z19a2
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4z19A (A:)
mytkilgtgsylpvqvrsnadlekmvdtsdewivtrtgirerriagldetvatmgfqaae
kalemagidkddigliivattssshafpssacqvqrmlgikdaasfdlaaacagftyals
vadqyvksgavkhaivigsdvlsraldpedrgtiilfgdgagavvlgaseqpgimsthlh
adgrygellalpypdrqqdqpayvtmagnevfkvavtelahivdetlqvnnldrtaldwl
vphqanlriisatakklgmgmdkvvitldrhgntsaasvpsafdeavrdgriqrgqlvll
eafgggftwgsalvrf

    Sequence, based on observed residues (ATOM records): (download) 
    >4z19A (A:)
mytkilgtgsylpvqvrsnadlekmvdtsdewivtrtgirerriagldetvatmgfqaae
kalemagidkddigliivattssshafpssacqvqrmlgikdaasfdlaaacagftyals
vadqyvksgavkhaivigsdvlsraldpedrgtiilfgdgagavvlgaseqpgimsthlh
adgrygellalpypayvtmagnevfkvavtelahivdetlqvnnldrtaldwlvphqanl
riisatakklgmgmdkvvitldrhgntsaasvpsafdeavrdgriqrgqlvlleafgggf
twgsalvrf