PDB entry 4yau

View 4yau on RCSB PDB site
Description: Reduced CYPOR mutant - G141del/E142N
Class: oxidoreductase
Keywords: cytochrome P450 reductase, FMN binding, semiquinone, OXIDOREDUCTASE
Deposited on 2015-02-17, released 2016-03-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-20, with a file datestamp of 2017-09-15.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NADPH--cytochrome P450 reductase
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Por
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00388 (Start-620)
      • engineered mutation (84)
    Domains in SCOPe 2.07: d4yaua1, d4yaua2, d4yaua3
  • Chain 'B':
    Compound: NADPH--cytochrome P450 reductase
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Por
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00388 (Start-620)
      • engineered mutation (84)
    Domains in SCOPe 2.07: d4yaub1, d4yaub2, d4yaub3
  • Heterogens: FMN, FAD, 2AM, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4yauA (A:)
iqttappvkessfvekmkktgrniivfygsqtgtaeefanrlskdahrygmrgmsadpee
ydladlsslpeidkslvvfcmatyngdptdnaqdfydwlqetdvdltgvkfavfglgnkt
yehfnamgkyvdqrleqlgaqrifelglgdddgnleedfitwreqfwpavceffgveatg
eessirqyelvvhedmdvakvytgemgrlksyenqkppfdaknpflaavtanrklnqgte
rhlmhleldisdskiryesgdhvavypandsalvnqigeilgadldvimslnnldeesnk
khpfpcpttyrtaltyylditnpprtnvlyelaqyasepseqehlhkmasssgegkelyl
swvvearrhilailqdypslrppidhlcellprlqaryysiassskvhpnsvhicavave
yeaksgrvnkgvatswlrakepagenggralvpmfvrksqfrlpfksttpvimvgpgtgi
apfmgfiqerawlreqgkevgetllyygcrrsdedylyreelarfhkdgaltqlnvafsr
eqahkvyvqhllkrdrehlwkliheggahiyvcgdarnmakdvqntfydivaefgpmeht
qavdyvkklmtkgrysldvws

    Sequence, based on observed residues (ATOM records): (download) 
    >4yauA (A:)
ppvkessfvekmkktgrniivfygsqtgtaeefanrlskdahrygmrgmsadpeeydlad
lsslpeidkslvvfcmatyngdptdnaqdfydwlqetdvdltgvkfavfglgnktyehfn
amgkyvdqrleqlgaqrifelglgdddgnleedfitwreqfwpavceffgveatssirqy
elvvhedmdvakvytgemgrlksyenqkppfdaknpflaavtanrklnqgterhlmhlel
disdskiryesgdhvavypandsalvnqigeilgadldvimslnnldeesnkkhpfpcpt
tyrtaltyylditnpprtnvlyelaqyasepseqehlhkmasssgegkelylswvvearr
hilailqdypslrppidhlcellprlqaryysiassskvhpnsvhicavaveyeaksgrv
nkgvatswlrakepagralvpmfvrksqfrlpfksttpvimvgpgtgiapfmgfiqeraw
lreqgkevgetllyygcrrsdedylyreelarfhkdgaltqlnvafsreqahkvyvqhll
krdrehlwkliheggahiyvcgdarnmakdvqntfydivaefgpmehtqavdyvkklmtk
grysldvws

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4yauB (B:)
iqttappvkessfvekmkktgrniivfygsqtgtaeefanrlskdahrygmrgmsadpee
ydladlsslpeidkslvvfcmatyngdptdnaqdfydwlqetdvdltgvkfavfglgnkt
yehfnamgkyvdqrleqlgaqrifelglgdddgnleedfitwreqfwpavceffgveatg
eessirqyelvvhedmdvakvytgemgrlksyenqkppfdaknpflaavtanrklnqgte
rhlmhleldisdskiryesgdhvavypandsalvnqigeilgadldvimslnnldeesnk
khpfpcpttyrtaltyylditnpprtnvlyelaqyasepseqehlhkmasssgegkelyl
swvvearrhilailqdypslrppidhlcellprlqaryysiassskvhpnsvhicavave
yeaksgrvnkgvatswlrakepagenggralvpmfvrksqfrlpfksttpvimvgpgtgi
apfmgfiqerawlreqgkevgetllyygcrrsdedylyreelarfhkdgaltqlnvafsr
eqahkvyvqhllkrdrehlwkliheggahiyvcgdarnmakdvqntfydivaefgpmeht
qavdyvkklmtkgrysldvws

    Sequence, based on observed residues (ATOM records): (download) 
    >4yauB (B:)
ssfvekmkktgrniivfygsqtgtaeefanrlskdahrygmrgmsadpeeydladlsslp
eidkslvvfcmatyngdptdnaqdfydwlqetdvdltgvkfavfglgnktyehfnamgky
vdqrleqlgaqrifelglgdddgnleedfitwreqfwpavceffgveatirqyelvvhed
mdvakvytgemgrlksyenqkppfdaknpflaavtanrklnqgterhlmhleldisdski
ryesgdhvavypandsalvnqigeilgadldvimslnnldeesnkkhpfpcpttyrtalt
yylditnpprtnvlyelaqyasepseqehlhkmasssgegkelylswvvearrhilailq
dypslrppidhlcellprlqaryysiassskvhpnsvhicavaveyeaksgrvnkgvats
wlrakepagralvpmfvrksqfrlpfksttpvimvgpgtgiapfmgfiqerawlreqgke
vgetllyygcrrsdedylyreelarfhkdgaltqlnvafsreqahkvyvqhllkrdrehl
wkliheggahiyvcgdarnmakdvqntfydivaefgpmehtqavdyvkklmtkgrysldv
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