PDB entry 4y2a

View 4y2a on RCSB PDB site
Description: Crystal Structure of Coxsackie Virus B3 3D polymerase in complex with GPC-N114 inhibitor
Class: transferase/transferase inhibitor
Keywords: Polymerase, Picornavirus, Coxsackievirus, GPC-N114, inhibitor, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2015-02-09, released 2015-04-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-04-08, with a file datestamp of 2015-04-03.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3D polymerase
    Species: Coxsackievirus B3 [TaxId:12072]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03313 (0-461)
      • expression tag (462-465)
    Domains in SCOPe 2.07: d4y2aa1, d4y2aa2
  • Heterogens: 1FS, SO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4y2aA (A:)
geiefiesskdagfpvintpsktklepsvfhqvfegnkepavlrsgdprlkanfeeaifs
kyignvnthvdeymleavdhyagqlatldistepmkledavygteglealdlttsagypy
valgikkrdilskktkdltklkecmdkyglnlpmvtyvkdelrsiekvakgksrlieass
lndsvamrqtfgnlyktfhlnpgvvtgsavgcdpdlfwskipvmldghliafdysgydas
lspvwfaclkmlleklgythketnyidylcnshhlyrdkhyfvrggmpsgcsgtsifnsm
inniiirtlmlkvykgidldqfrmiaygddviasypwpidasllaeagkgyglimtpadk
gecfnevtwtnatflkryfradeqypflvhpvmpmkdihesirwtkdpkntqdhvrslcl
lawhngeheyeefirkirsvpvgrcltlpafstlrrkwldsfhhhh