PDB entry 4x8s

View 4x8s on RCSB PDB site
Description: factor viia in complex with the inhibitor 4-bromo-2-methoxyphenol
Class: hydrolase/hydrolase inhibitor
Keywords: glycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium- binding
Deposited on 2014-12-10, released 2015-03-25
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-04-08, with a file datestamp of 2015-04-03.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Factor VIIa (Heavy Chain)
    Species: Homo sapiens [TaxId:9606]
    Gene: F7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4x8sh_
  • Chain 'L':
    Compound: Factor VIIa (Light Chain)
    Species: Homo sapiens [TaxId:9606]
    Gene: F7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4x8sl_
  • Heterogens: 3Z7, CA, SO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4x8sH (H:)
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

    Sequence, based on observed residues (ATOM records): (download) 
    >4x8sH (H:)
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrpniteymfcagysdgsk
dsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmrseprp
gvllrapfp

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4x8sL (L:)
icvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipilekr