PDB entry 4woq

View 4woq on RCSB PDB site
Description: Crystal Structures of CdNal from Clostridium difficile in complex with ketobutyric
Class: lyase
Keywords: aldolase, thermostable, LYASE
Deposited on 2014-10-16, released 2015-10-21
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-10-21, with a file datestamp of 2015-10-16.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: n-acetylneuraminate lyase
    Species: Peptoclostridium difficile NAP08 [TaxId:525259]
    Gene: CdNal
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4woqa_
  • Chain 'B':
    Compound: n-acetylneuraminate lyase
    Species: Peptoclostridium difficile NAP08 [TaxId:525259]
    Gene: CdNal
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4woqb_
  • Chain 'C':
    Compound: n-acetylneuraminate lyase
    Species: Peptoclostridium difficile NAP08 [TaxId:525259]
    Gene: CdNal
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4woqc_
  • Chain 'D':
    Compound: n-acetylneuraminate lyase
    Species: Peptoclostridium difficile NAP08 [TaxId:525259]
    Gene: CdNal
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4woqd_
  • Chain 'E':
    Compound: n-acetylneuraminate lyase
    Species: Peptoclostridium difficile NAP08 [TaxId:525259]
    Gene: CdNal
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4woqe_
  • Chain 'F':
    Compound: n-acetylneuraminate lyase
    Species: Peptoclostridium difficile NAP08 [TaxId:525259]
    Gene: CdNal
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4woqf_
  • Chain 'G':
    Compound: n-acetylneuraminate lyase
    Species: Peptoclostridium difficile NAP08 [TaxId:525259]
    Gene: CdNal
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4woqg_
  • Chain 'H':
    Compound: n-acetylneuraminate lyase
    Species: Peptoclostridium difficile NAP08 [TaxId:525259]
    Gene: CdNal
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4woqh_
  • Heterogens: 2KT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4woqA (A:)
mkikiggkdmrttdmkgiysallvsfdkegninekglrqiirhnidvckvdglyvggstg
enfmlstdekkrifeiakdevkeeikliaqvgsvnlkeavelakfttdlgydaisavtpf
yykfdfeeikhyyntiinsvdnrliiysipfltgvdmsldqfgelfenekiigvkftaad
fyllermrktfpnklifagfdemmlpatvlgvdgaigstfnvngvrarqifeltknekis
ealevqhvtndlitdilgnglyqtikllleeqgveagycrqpmkeatdemksrakeiyrk
yf

    Sequence, based on observed residues (ATOM records): (download) 
    >4woqA (A:)
tdmkgiysallvsfdkegninekglrqiirhnidvckvdglyvggstgenfmlstdekkr
ifeiakdevkeeikliaqvgsvnlkeavelakfttdlgydaisavtpfyykfdfeeikhy
yntiinsvdnrliiysipfltgvdmsldqfgelfenekiigvkftaadfyllermrktfp
nklifagfdemmlpatvlgvdgaigstfnvngvrarqifeltknekisealevqhvtndl
itdilgnglyqtikllleeqgveagycrqpmkeatdemksrakeiyrkyf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4woqB (B:)
mkikiggkdmrttdmkgiysallvsfdkegninekglrqiirhnidvckvdglyvggstg
enfmlstdekkrifeiakdevkeeikliaqvgsvnlkeavelakfttdlgydaisavtpf
yykfdfeeikhyyntiinsvdnrliiysipfltgvdmsldqfgelfenekiigvkftaad
fyllermrktfpnklifagfdemmlpatvlgvdgaigstfnvngvrarqifeltknekis
ealevqhvtndlitdilgnglyqtikllleeqgveagycrqpmkeatdemksrakeiyrk
yf

    Sequence, based on observed residues (ATOM records): (download) 
    >4woqB (B:)
tdmkgiysallvsfdkegninekglrqiirhnidvckvdglyvggstgenfmlstdekkr
ifeiakdevkeeikliaqvgsvnlkeavelakfttdlgydaisavtpfyykfdfeeikhy
yntiinsvdnrliiysipfltgvdmsldqfgelfenekiigvkftaadfyllermrktfp
nklifagfdemmlpatvlgvdgaigstfnvngvrarqifeltknekisealevqhvtndl
itdilgnglyqtikllleeqgveagycrqpmkeatdemksrakeiyrkyf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4woqC (C:)
mkikiggkdmrttdmkgiysallvsfdkegninekglrqiirhnidvckvdglyvggstg
enfmlstdekkrifeiakdevkeeikliaqvgsvnlkeavelakfttdlgydaisavtpf
yykfdfeeikhyyntiinsvdnrliiysipfltgvdmsldqfgelfenekiigvkftaad
fyllermrktfpnklifagfdemmlpatvlgvdgaigstfnvngvrarqifeltknekis
ealevqhvtndlitdilgnglyqtikllleeqgveagycrqpmkeatdemksrakeiyrk
yf

    Sequence, based on observed residues (ATOM records): (download) 
    >4woqC (C:)
tdmkgiysallvsfdkegninekglrqiirhnidvckvdglyvggstgenfmlstdekkr
ifeiakdevkeeikliaqvgsvnlkeavelakfttdlgydaisavtpfyykfdfeeikhy
yntiinsvdnrliiysipfltgvdmsldqfgelfenekiigvkftaadfyllermrktfp
nklifagfdemmlpatvlgvdgaigstfnvngvrarqifeltknekisealevqhvtndl
itdilgnglyqtikllleeqgveagycrqpmkeatdemksrakeiyrkyf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4woqD (D:)
mkikiggkdmrttdmkgiysallvsfdkegninekglrqiirhnidvckvdglyvggstg
enfmlstdekkrifeiakdevkeeikliaqvgsvnlkeavelakfttdlgydaisavtpf
yykfdfeeikhyyntiinsvdnrliiysipfltgvdmsldqfgelfenekiigvkftaad
fyllermrktfpnklifagfdemmlpatvlgvdgaigstfnvngvrarqifeltknekis
ealevqhvtndlitdilgnglyqtikllleeqgveagycrqpmkeatdemksrakeiyrk
yf

    Sequence, based on observed residues (ATOM records): (download) 
    >4woqD (D:)
tdmkgiysallvsfdkegninekglrqiirhnidvckvdglyvggstgenfmlstdekkr
ifeiakdevkeeikliaqvgsvnlkeavelakfttdlgydaisavtpfyykfdfeeikhy
yntiinsvdnrliiysipfltgvdmsldqfgelfenekiigvkftaadfyllermrktfp
nklifagfdemmlpatvlgvdgaigstfnvngvrarqifeltknekisealevqhvtndl
itdilgnglyqtikllleeqgveagycrqpmkeatdemksrakeiyrkyf

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4woqE (E:)
mkikiggkdmrttdmkgiysallvsfdkegninekglrqiirhnidvckvdglyvggstg
enfmlstdekkrifeiakdevkeeikliaqvgsvnlkeavelakfttdlgydaisavtpf
yykfdfeeikhyyntiinsvdnrliiysipfltgvdmsldqfgelfenekiigvkftaad
fyllermrktfpnklifagfdemmlpatvlgvdgaigstfnvngvrarqifeltknekis
ealevqhvtndlitdilgnglyqtikllleeqgveagycrqpmkeatdemksrakeiyrk
yf

    Sequence, based on observed residues (ATOM records): (download) 
    >4woqE (E:)
tdmkgiysallvsfdkegninekglrqiirhnidvckvdglyvggstgenfmlstdekkr
ifeiakdevkeeikliaqvgsvnlkeavelakfttdlgydaisavtpfyykfdfeeikhy
yntiinsvdnrliiysipfltgvdmsldqfgelfenekiigvkftaadfyllermrktfp
nklifagfdemmlpatvlgvdgaigstfnvngvrarqifeltknekisealevqhvtndl
itdilgnglyqtikllleeqgveagycrqpmkeatdemksrakeiyrkyf

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4woqF (F:)
mkikiggkdmrttdmkgiysallvsfdkegninekglrqiirhnidvckvdglyvggstg
enfmlstdekkrifeiakdevkeeikliaqvgsvnlkeavelakfttdlgydaisavtpf
yykfdfeeikhyyntiinsvdnrliiysipfltgvdmsldqfgelfenekiigvkftaad
fyllermrktfpnklifagfdemmlpatvlgvdgaigstfnvngvrarqifeltknekis
ealevqhvtndlitdilgnglyqtikllleeqgveagycrqpmkeatdemksrakeiyrk
yf

    Sequence, based on observed residues (ATOM records): (download) 
    >4woqF (F:)
tdmkgiysallvsfdkegninekglrqiirhnidvckvdglyvggstgenfmlstdekkr
ifeiakdevkeeikliaqvgsvnlkeavelakfttdlgydaisavtpfyykfdfeeikhy
yntiinsvdnrliiysipfltgvdmsldqfgelfenekiigvkftaadfyllermrktfp
nklifagfdemmlpatvlgvdgaigstfnvngvrarqifeltknekisealevqhvtndl
itdilgnglyqtikllleeqgveagycrqpmkeatdemksrakeiyrkyf

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4woqG (G:)
mkikiggkdmrttdmkgiysallvsfdkegninekglrqiirhnidvckvdglyvggstg
enfmlstdekkrifeiakdevkeeikliaqvgsvnlkeavelakfttdlgydaisavtpf
yykfdfeeikhyyntiinsvdnrliiysipfltgvdmsldqfgelfenekiigvkftaad
fyllermrktfpnklifagfdemmlpatvlgvdgaigstfnvngvrarqifeltknekis
ealevqhvtndlitdilgnglyqtikllleeqgveagycrqpmkeatdemksrakeiyrk
yf

    Sequence, based on observed residues (ATOM records): (download) 
    >4woqG (G:)
tdmkgiysallvsfdkegninekglrqiirhnidvckvdglyvggstgenfmlstdekkr
ifeiakdevkeeikliaqvgsvnlkeavelakfttdlgydaisavtpfyykfdfeeikhy
yntiinsvdnrliiysipfltgvdmsldqfgelfenekiigvkftaadfyllermrktfp
nklifagfdemmlpatvlgvdgaigstfnvngvrarqifeltknekisealevqhvtndl
itdilgnglyqtikllleeqgveagycrqpmkeatdemksrakeiyrkyf

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4woqH (H:)
mkikiggkdmrttdmkgiysallvsfdkegninekglrqiirhnidvckvdglyvggstg
enfmlstdekkrifeiakdevkeeikliaqvgsvnlkeavelakfttdlgydaisavtpf
yykfdfeeikhyyntiinsvdnrliiysipfltgvdmsldqfgelfenekiigvkftaad
fyllermrktfpnklifagfdemmlpatvlgvdgaigstfnvngvrarqifeltknekis
ealevqhvtndlitdilgnglyqtikllleeqgveagycrqpmkeatdemksrakeiyrk
yf

    Sequence, based on observed residues (ATOM records): (download) 
    >4woqH (H:)
tdmkgiysallvsfdkegninekglrqiirhnidvckvdglyvggstgenfmlstdekkr
ifeiakdevkeeikliaqvgsvnlkeavelakfttdlgydaisavtpfyykfdfeeikhy
yntiinsvdnrliiysipfltgvdmsldqfgelfenekiigvkftaadfyllermrktfp
nklifagfdemmlpatvlgvdgaigstfnvngvrarqifeltknekisealevqhvtndl
itdilgnglyqtikllleeqgveagycrqpmkeatdemksrakeiyrkyf