PDB entry 4s1e

View 4s1e on RCSB PDB site
Description: Crystal structure of cyclophilin mutant L120A from Leishmania donovani at 2.22 angstrom.
Class: isomerase
Keywords: Cytosol, isomerase
Deposited on 2015-01-13, released 2015-03-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-03-11, with a file datestamp of 2015-03-06.
Experiment type: XRAY
Resolution: 2.22 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: peptidyl-prolyl cis-trans isomerase
    Species: Leishmania donovani [TaxId:5661]
    Gene: CYP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9U9R3 (6-171)
      • see remark 999 (65)
      • see remark 999 (96)
      • engineered mutation (104)
    Domains in SCOPe 2.07: d4s1ea_
  • Chain 'B':
    Compound: peptidyl-prolyl cis-trans isomerase
    Species: Leishmania donovani [TaxId:5661]
    Gene: CYP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9U9R3 (6-171)
      • see remark 999 (65)
      • see remark 999 (96)
      • engineered mutation (104)
    Domains in SCOPe 2.07: d4s1eb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4s1eA (A:)
hhhhhhepevtakvyfdvmidseplgritiglfgkdaplttenfrqlctgehgfgykdsi
fhrvipnfmiqggdftnfdgtggksiygekfadenlkvkhfvgaasmanagpntngsqff
ittaptpwldgrhvvfgkvldgmdvvlriektktnshdrpvkpvkivasgel

    Sequence, based on observed residues (ATOM records): (download) 
    >4s1eA (A:)
epevtakvyfdvmidseplgritiglfgkdaplttenfrqlctgehgfgykdsifhrvip
nfmiqggdftnfdgtggksiygekfadenlkvkhfvgaasmanagpntngsqffittapt
pwldgrhvvfgkvldgmdvvlriektktnshdrpvkpvkivasgel

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4s1eB (B:)
hhhhhhepevtakvyfdvmidseplgritiglfgkdaplttenfrqlctgehgfgykdsi
fhrvipnfmiqggdftnfdgtggksiygekfadenlkvkhfvgaasmanagpntngsqff
ittaptpwldgrhvvfgkvldgmdvvlriektktnshdrpvkpvkivasgel

    Sequence, based on observed residues (ATOM records): (download) 
    >4s1eB (B:)
epevtakvyfdvmidseplgritiglfgkdaplttenfrqlctgehgfgykdsifhrvip
nfmiqggdftnfdgtggksiygekfadenlkvkhfvgaasmanagpntngsqffittapt
pwldgrhvvfgkvldgmdvvlriektktnshdrpvkpvkivasgel