PDB entry 4r7l

View 4r7l on RCSB PDB site
Description: Structure of Human Leukotriene A4 Hydrolase in complex with inhibitor H1
Class: hydrolase/hydrolase inhibitor
Keywords: Leukotriene A4, Metalloprotein, Protease, Zinc binding, Aminopeptidase activity, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2014-08-27, released 2015-11-25
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-11-25, with a file datestamp of 2015-11-20.
Experiment type: XRAY
Resolution: 1.66 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Leukotriene A-4 hydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: LTA4H, LTA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4r7la1, d4r7la2, d4r7la3
  • Heterogens: ZN, YB, GOL, ACT, IMD, SHH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4r7lA (A:)
mgsshhhhhhssglvprgshmpeivdtcslaspasvcrtkhlhlrcsvdftrrtltgtaa
ltvqsqednlrslvldtkdltiekvvingqevkyalgerqsykgspmeislpialsknqe
ivieisfetspkssalqwltpeqtsgkehpylfsqcqaihcrailpcqdtpsvkltytae
vsvpkelvalmsairdgetpdpedpsrkiykfiqkvpipcylialvvgalesrqigprtl
vwsekeqveksayefsetesmlkiaedlggpyvwgqydllvlppsfpyggmenpcltfvt
ptllagdkslsnviaheishswtgnlvtnktwdhfwlneghtvylerhicgrlfgekfrh
fnalggwgelqnsvktfgethpftklvvdltdidpdvayssvpyekgfallfyleqllgg
peiflgflkayvekfsyksittddwkdflysyfkdkvdvlnqvdwnawlyspglppikpn
ydmtltnacialsqrwitakeddlnsfnatdlkdlsshqlneflaqtlqraplplghikr
mqevynfnainnseirfrwlrlciqskwedaiplalkmateqgrmkftrplfkdlaafdk
shdqavrtyqehkasmhpvtamlvgkdlkvd

    Sequence, based on observed residues (ATOM records): (download) 
    >4r7lA (A:)
ivdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdltie
kvvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwltpeq
tsgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetpdpe
dpsrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetesmlk
iaedlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnviaheishswt
gnlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfgethpf
tklvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksittd
dwkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitakedd
lnsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwlrlc
iqskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvtaml
vgkdlkv