PDB entry 4r1r

View 4r1r on RCSB PDB site
Description: ribonucleotide reductase r1 protein with substrate, GDP and effector dttp from escherichia coli
Class: complex (oxidoreductase/peptide)
Keywords: ribonucleotide reductase, deoxyribonucleotide synthesis, radical chemistry, allosteric regulation, specificity, complex (oxidoreductase/peptide)
Deposited on 1997-07-22, released 1998-01-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.278
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ribonucleotide reductase r1 protein
    Species: Escherichia coli [TaxId:562]
    Gene: NRDA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00452
      • engineered (291)
    Domains in SCOPe 2.07: d4r1ra1, d4r1ra2
  • Chain 'B':
    Compound: ribonucleotide reductase r1 protein
    Species: Escherichia coli [TaxId:562]
    Gene: NRDA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00452
      • engineered (291)
    Domains in SCOPe 2.07: d4r1rb1, d4r1rb2
  • Chain 'C':
    Compound: ribonucleotide reductase r1 protein
    Species: Escherichia coli [TaxId:562]
    Gene: NRDA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00452
      • engineered (291)
    Domains in SCOPe 2.07: d4r1rc1, d4r1rc2
  • Chain 'D':
    Compound: ribonucleotide reductase r2 protein
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: ribonucleotide reductase r2 protein
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: ribonucleotide reductase r2 protein
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: ribonucleotide reductase r2 protein
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: TTP, GDP

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4r1rA (A:)
mnqnllvtkrdgsterinldkihrvldwaaeglhnvsisqvelrshiqfydgiktsdihe
tiikaaadlisrdapdyqylaarlaifhlrkkaygqfeppalydhvvkmvemgkydnhll
edyteeefkqmdtfidhdrdmtfsyaavkqlegkylvqnrvtgeiyesaqflyilvaacl
fsnypretrlqyvkrfydavstfkislptpimsgvrtptrqfsscvliecgdsldsinat
ssaivkyvsqragiginagriralgspirggeafhtgcipfykhfqtavksasqggvrgg
aatlfypmwhlevesllvlknnrgvegnrvrhmdygvqinklmytrllkgeditlfspsd
vpglydaffadqeeferlytkyekddsirkqrvkavelfslmmqerastgriyiqnvdhc
nthspfdpaiapvrqsnlcleialptkplndvndengeialctlsafnlgainnldelee
lailavraldalldyqdypipaakrgamgrrtlgigvinfayylakhgkrysdgsannlt
hktfeaiqyyllkasnelakeqgacpwfnettyakgilpidtykkdldtianeplhydwe
alresikthglrnstlsalmpsetssqisnatngiepprgyvsikaskdgilrqvvpdye
hlhdayellwempgndgylqlvgimqkfidqsisantnydpsrfpsgkvpmqqllkdllt
aykfgvktlyyqntrdgaedaqddlvpsiqddgcesgacki

    Sequence, based on observed residues (ATOM records): (download) 
    >4r1rA (A:)
llvtkrdgsterinldkihrvldwaaeglhnvsisqvelrshiqfydgiktsdihetiik
aaadlisrdapdyqylaarlaifhlrkkaygqfeppalydhvvkmvemgkydnhlledyt
eeefkqmdtfidhdrdmtfsyaavkqlegkylvqnrvtgeiyesaqflyilvaaclfsny
pretrlqyvkrfydavstfkislptpimsgvrtptrqfsscvliecgdsldsinatssai
vkyvsqragiginagriralgspirggeafhtgcipfykhfqtavksasqggvrggaatl
fypmwhlevesllvlknnrgvegnrvrhmdygvqinklmytrllkgeditlfspsdvpgl
ydaffadqeeferlytkyekddsirkqrvkavelfslmmqerastgriyiqnvdhcnths
pfdpaiapvrqsnlcleialptkplndvndengeialctlsafnlgainnldeleelail
avraldalldyqdypipaakrgamgrrtlgigvinfayylakhgkrysdgsannlthktf
eaiqyyllkasnelakeqgacpwfnettyakgilpidtykkdldtianeplhydwealre
sikthglrnstlsalmpsetssqisnatngiepprgyvsikaskdgilrqvvpdyehlhd
ayellwempgndgylqlvgimqkfidqsisantnydpsrfpsgkvpmqqllkdlltaykf
gvktlyyqntrdg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4r1rB (B:)
mnqnllvtkrdgsterinldkihrvldwaaeglhnvsisqvelrshiqfydgiktsdihe
tiikaaadlisrdapdyqylaarlaifhlrkkaygqfeppalydhvvkmvemgkydnhll
edyteeefkqmdtfidhdrdmtfsyaavkqlegkylvqnrvtgeiyesaqflyilvaacl
fsnypretrlqyvkrfydavstfkislptpimsgvrtptrqfsscvliecgdsldsinat
ssaivkyvsqragiginagriralgspirggeafhtgcipfykhfqtavksasqggvrgg
aatlfypmwhlevesllvlknnrgvegnrvrhmdygvqinklmytrllkgeditlfspsd
vpglydaffadqeeferlytkyekddsirkqrvkavelfslmmqerastgriyiqnvdhc
nthspfdpaiapvrqsnlcleialptkplndvndengeialctlsafnlgainnldelee
lailavraldalldyqdypipaakrgamgrrtlgigvinfayylakhgkrysdgsannlt
hktfeaiqyyllkasnelakeqgacpwfnettyakgilpidtykkdldtianeplhydwe
alresikthglrnstlsalmpsetssqisnatngiepprgyvsikaskdgilrqvvpdye
hlhdayellwempgndgylqlvgimqkfidqsisantnydpsrfpsgkvpmqqllkdllt
aykfgvktlyyqntrdgaedaqddlvpsiqddgcesgacki

    Sequence, based on observed residues (ATOM records): (download) 
    >4r1rB (B:)
llvtkrdgsterinldkihrvldwaaeglhnvsisqvelrshiqfydgiktsdihetiik
aaadlisrdapdyqylaarlaifhlrkkaygqfeppalydhvvkmvemgkydnhlledyt
eeefkqmdtfidhdrdmtfsyaavkqlegkylvqnrvtgeiyesaqflyilvaaclfsny
pretrlqyvkrfydavstfkislptpimsgvrtptrqfsscvliecgdsldsinatssai
vkyvsqragiginagriralgspirggeafhtgcipfykhfqtavksasqggvrggaatl
fypmwhlevesllvlknnrgvegnrvrhmdygvqinklmytrllkgeditlfspsdvpgl
ydaffadqeeferlytkyekddsirkqrvkavelfslmmqerastgriyiqnvdhcnths
pfdpaiapvrqsnlcleialptkplndvndengeialctlsafnlgainnldeleelail
avraldalldyqdypipaakrgamgrrtlgigvinfayylakhgkrysdgsannlthktf
eaiqyyllkasnelakeqgacpwfnettyakgilpidtykkdldtianeplhydwealre
sikthglrnstlsalmpsetssqisnatngiepprgyvsikaskdgilrqvvpdyehlhd
ayellwempgndgylqlvgimqkfidqsisantnydpsrfpsgkvpmqqllkdlltaykf
gvktlyyqntrdg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4r1rC (C:)
mnqnllvtkrdgsterinldkihrvldwaaeglhnvsisqvelrshiqfydgiktsdihe
tiikaaadlisrdapdyqylaarlaifhlrkkaygqfeppalydhvvkmvemgkydnhll
edyteeefkqmdtfidhdrdmtfsyaavkqlegkylvqnrvtgeiyesaqflyilvaacl
fsnypretrlqyvkrfydavstfkislptpimsgvrtptrqfsscvliecgdsldsinat
ssaivkyvsqragiginagriralgspirggeafhtgcipfykhfqtavksasqggvrgg
aatlfypmwhlevesllvlknnrgvegnrvrhmdygvqinklmytrllkgeditlfspsd
vpglydaffadqeeferlytkyekddsirkqrvkavelfslmmqerastgriyiqnvdhc
nthspfdpaiapvrqsnlcleialptkplndvndengeialctlsafnlgainnldelee
lailavraldalldyqdypipaakrgamgrrtlgigvinfayylakhgkrysdgsannlt
hktfeaiqyyllkasnelakeqgacpwfnettyakgilpidtykkdldtianeplhydwe
alresikthglrnstlsalmpsetssqisnatngiepprgyvsikaskdgilrqvvpdye
hlhdayellwempgndgylqlvgimqkfidqsisantnydpsrfpsgkvpmqqllkdllt
aykfgvktlyyqntrdgaedaqddlvpsiqddgcesgacki

    Sequence, based on observed residues (ATOM records): (download) 
    >4r1rC (C:)
llvtkrdgsterinldkihrvldwaaeglhnvsisqvelrshiqfydgiktsdihetiik
aaadlisrdapdyqylaarlaifhlrkkaygqfeppalydhvvkmvemgkydnhlledyt
eeefkqmdtfidhdrdmtfsyaavkqlegkylvqnrvtgeiyesaqflyilvaaclfsny
pretrlqyvkrfydavstfkislptpimsgvrtptrqfsscvliecgdsldsinatssai
vkyvsqragiginagriralgspirggeafhtgcipfykhfqtavksasqggvrggaatl
fypmwhlevesllvlknnrgvegnrvrhmdygvqinklmytrllkgeditlfspsdvpgl
ydaffadqeeferlytkyekddsirkqrvkavelfslmmqerastgriyiqnvdhcnths
pfdpaiapvrqsnlcleialptkplndvndengeialctlsafnlgainnldeleelail
avraldalldyqdypipaakrgamgrrtlgigvinfayylakhgkrysdgsannlthktf
eaiqyyllkasnelakeqgacpwfnettyakgilpidtykkdldtianeplhydwealre
sikthglrnstlsalmpsetssqisnatngiepprgyvsikaskdgilrqvvpdyehlhd
ayellwempgndgylqlvgimqkfidqsisantnydpsrfpsgkvpmqqllkdlltaykf
gvktlyyqntrdg

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'P':
    No sequence available.