PDB entry 4ogw

View 4ogw on RCSB PDB site
Description: Structure of a human CD38 mutant complexed with NMN
Class: hydrolase
Keywords: ADP-ribosyl cyclase, HYDROLASE
Deposited on 2014-01-16, released 2014-10-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-12-17, with a file datestamp of 2014-12-12.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.201
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ADP-ribosyl cyclase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD38
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28907 (2-End)
      • expression tag (1)
      • engineered mutation (56)
      • engineered mutation (120)
      • engineered mutation (165)
      • engineered mutation (175)
      • engineered mutation (182)
    Domains in SCOPe 2.07: d4ogwa1, d4ogwa2
  • Heterogens: NMN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ogwA (A:)
gswrqqwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcdite
edyqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgef
atskinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfg
svqvhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckniyrpdk
flqcvknpedssctsei

    Sequence, based on observed residues (ATOM records): (download) 
    >4ogwA (A:)
swrqqwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcditee
dyqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgefa
tskinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfgs
vqvhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckniyrpdkf
lqcvknped