PDB entry 4o9a

View 4o9a on RCSB PDB site
Description: Crystal structure of Beta-ketothiolase (PhaA) from Ralstonia eutropha H16
Class: transferase
Keywords: acetoacetyl-coa transferase, TRANSFERASE, PHB biosynthesis, Acyltransferase Transferase
Deposited on 2014-01-02, released 2015-02-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 1.52 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acetyl-CoA acetyltransferase
    Species: Ralstonia eutropha [TaxId:381666]
    Gene: H16_A1438, phaA, phbA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14611 (6-397)
      • engineered mutation (92)
    Domains in SCOPe 2.07: d4o9aa1, d4o9aa2
  • Chain 'B':
    Compound: Acetyl-CoA acetyltransferase
    Species: Ralstonia eutropha [TaxId:381666]
    Gene: H16_A1438, phaA, phbA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14611 (6-397)
      • engineered mutation (92)
    Domains in SCOPe 2.07: d4o9ab1, d4o9ab2
  • Chain 'C':
    Compound: Acetyl-CoA acetyltransferase
    Species: Ralstonia eutropha [TaxId:381666]
    Gene: H16_A1438, phaA, phbA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14611 (6-397)
      • engineered mutation (92)
    Domains in SCOPe 2.07: d4o9ac1, d4o9ac2
  • Chain 'D':
    Compound: Acetyl-CoA acetyltransferase
    Species: Ralstonia eutropha [TaxId:381666]
    Gene: H16_A1438, phaA, phbA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14611 (6-397)
      • engineered mutation (92)
    Domains in SCOPe 2.07: d4o9ad1, d4o9ad2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4o9aA (A:)
hhhhhhtdvvivsaartavgkfggslakipapelgavvikaaleragvkpeqvsevimgq
vltagsgqnparqaaikaglpamvpamtinkvsgsglkavmlaanaimagdaeivvaggq
enmsaaphvlpgsrdgfrmgdaklvdtmivdglwdvynqyhmgitaenvakeygitreaq
defavgsqnkaeaaqkagkfdeeivpvlipqrkgdpvafktdefvrqgatldsmsglkpa
fdkagtvtaanasglndgaaavvvmsaakakelgltplatiksyanagvdpkvmgmgpvp
askralsraewtpqdldlmeineafaaqalavhqqmgwdtskvnvnggaiaighpigasg
crilvtllhemkrrdakkglaslcigggmgvalaverk

    Sequence, based on observed residues (ATOM records): (download) 
    >4o9aA (A:)
tdvvivsaartavgkfggslakipapelgavvikaaleragvkpeqvsevimgqvltags
gqnparqaaikaglpamvpamtinkvsgsglkavmlaanaimagdaeivvaggqenmsaa
phvlpgsrdgfrmgdaklvdtmivdglwdvynqyhmgitaenvakeygitreaqdefavg
sqnkaeaaqkagkfdeeivpvlipqrkgdpvafktdefvrqgatldsmsglkpafdkagt
vtaanasglndgaaavvvmsaakakelgltplatiksyanagvdpkvmgmgpvpaskral
sraewtpqdldlmeineafaaqalavhqqmgwdtskvnvnggaiaighpigasgcrilvt
llhemkrrdakkglaslcigggmgvalaverk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4o9aB (B:)
hhhhhhtdvvivsaartavgkfggslakipapelgavvikaaleragvkpeqvsevimgq
vltagsgqnparqaaikaglpamvpamtinkvsgsglkavmlaanaimagdaeivvaggq
enmsaaphvlpgsrdgfrmgdaklvdtmivdglwdvynqyhmgitaenvakeygitreaq
defavgsqnkaeaaqkagkfdeeivpvlipqrkgdpvafktdefvrqgatldsmsglkpa
fdkagtvtaanasglndgaaavvvmsaakakelgltplatiksyanagvdpkvmgmgpvp
askralsraewtpqdldlmeineafaaqalavhqqmgwdtskvnvnggaiaighpigasg
crilvtllhemkrrdakkglaslcigggmgvalaverk

    Sequence, based on observed residues (ATOM records): (download) 
    >4o9aB (B:)
tdvvivsaartavgkfggslakipapelgavvikaaleragvkpeqvsevimgqvltags
gqnparqaaikaglpamvpamtinkvsgsglkavmlaanaimagdaeivvaggqenmsaa
phvlpgsrdgfrmgdaklvdtmivdglwdvynqyhmgitaenvakeygitreaqdefavg
sqnkaeaaqkagkfdeeivpvlipqrkgdpvafktdefvrqgatldsmsglkpafdkagt
vtaanasglndgaaavvvmsaakakelgltplatiksyanagvdpkvmgmgpvpaskral
sraewtpqdldlmeineafaaqalavhqqmgwdtskvnvnggaiaighpigasgcrilvt
llhemkrrdakkglaslcigggmgvalaverk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4o9aC (C:)
hhhhhhtdvvivsaartavgkfggslakipapelgavvikaaleragvkpeqvsevimgq
vltagsgqnparqaaikaglpamvpamtinkvsgsglkavmlaanaimagdaeivvaggq
enmsaaphvlpgsrdgfrmgdaklvdtmivdglwdvynqyhmgitaenvakeygitreaq
defavgsqnkaeaaqkagkfdeeivpvlipqrkgdpvafktdefvrqgatldsmsglkpa
fdkagtvtaanasglndgaaavvvmsaakakelgltplatiksyanagvdpkvmgmgpvp
askralsraewtpqdldlmeineafaaqalavhqqmgwdtskvnvnggaiaighpigasg
crilvtllhemkrrdakkglaslcigggmgvalaverk

    Sequence, based on observed residues (ATOM records): (download) 
    >4o9aC (C:)
tdvvivsaartavgkfggslakipapelgavvikaaleragvkpeqvsevimgqvltags
gqnparqaaikaglpamvpamtinkvsgsglkavmlaanaimagdaeivvaggqenmsaa
phvlpgsrdgfrmgdaklvdtmivdglwdvynqyhmgitaenvakeygitreaqdefavg
sqnkaeaaqkagkfdeeivpvlipqrkgdpvafktdefvrqgatldsmsglkpafdkagt
vtaanasglndgaaavvvmsaakakelgltplatiksyanagvdpkvmgmgpvpaskral
sraewtpqdldlmeineafaaqalavhqqmgwdtskvnvnggaiaighpigasgcrilvt
llhemkrrdakkglaslcigggmgvalaverk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4o9aD (D:)
hhhhhhtdvvivsaartavgkfggslakipapelgavvikaaleragvkpeqvsevimgq
vltagsgqnparqaaikaglpamvpamtinkvsgsglkavmlaanaimagdaeivvaggq
enmsaaphvlpgsrdgfrmgdaklvdtmivdglwdvynqyhmgitaenvakeygitreaq
defavgsqnkaeaaqkagkfdeeivpvlipqrkgdpvafktdefvrqgatldsmsglkpa
fdkagtvtaanasglndgaaavvvmsaakakelgltplatiksyanagvdpkvmgmgpvp
askralsraewtpqdldlmeineafaaqalavhqqmgwdtskvnvnggaiaighpigasg
crilvtllhemkrrdakkglaslcigggmgvalaverk

    Sequence, based on observed residues (ATOM records): (download) 
    >4o9aD (D:)
tdvvivsaartavgkfggslakipapelgavvikaaleragvkpeqvsevimgqvltags
gqnparqaaikaglpamvpamtinkvsgsglkavmlaanaimagdaeivvaggqenmsaa
phvlpgsrdgfrmgdaklvdtmivdglwdvynqyhmgitaenvakeygitreaqdefavg
sqnkaeaaqkagkfdeeivpvlipqrkgdpvafktdefvrqgatldsmsglkpafdkagt
vtaanasglndgaaavvvmsaakakelgltplatiksyanagvdpkvmgmgpvpaskral
sraewtpqdldlmeineafaaqalavhqqmgwdtskvnvnggaiaighpigasgcrilvt
llhemkrrdakkglaslcigggmgvalaverk