PDB entry 4nrt

View 4nrt on RCSB PDB site
Description: Human Norovirus polymerase bound to Compound 6 (suramin derivative)
Class: viral protein/transcription inhibitor
Keywords: RNA dependent RNA Polymerase, VIRAL PROTEIN-TRANSCRIPTION INHIBITOR complex
Deposited on 2013-11-27, released 2014-10-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-10-15, with a file datestamp of 2014-10-10.
Experiment type: XRAY
Resolution: 2.02 Å
R-factor: 0.164
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hNV-RdRp
    Species: Norwalk-like virus [TaxId:95340]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0ZNP5
      • conflict (153)
      • conflict (211)
    Domains in SCOPe 2.07: d4nrta_
  • Heterogens: 2NG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4nrtA (A:)
mggdskgtycgapilgpgsapklstktkfwrssttplppgtyepaylggkdprvkggpsl
qqvmrdqlkpfteprgkppkpsvleaakktiinvleqtidppekwsftqacasldkttss
ghphhmrkndcwngesftgkladqaskanlmfeggknmtpvytgalkdelvktdkiygki
kkrllwgsdlatmircarafgglmdelkahcvtlpirvgmnmnedgpiiferhsrykyhy
dadysrwdstqqravlaaaleimvkfssephlaqvvaedllspsvvdvgdfkisineglp
sgvpctsqwnsiahwlltlcalsevtnlspdiiqanslfsfygddeivstdikldpeklt
aklkeyglkptrpdktegplvisedlngltflrrtvtrdpagwfgkleqssilrqmywtr
gpnhedpsetmiphsqrpiqlmsllgeaalhgpafyskisklviaelkeggmdfyvprqe
pmfrwmrfsdlstwegdrnlapsfvnedgvevdklaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4nrtA (A:)
gtycgapilgpgsapklstktkfwrssttplppgtyepaylggkdprvkggpslqqvmrd
qlkpfteprgkppkpsvleaakktiinvleqtidppekwsftqacasldkttssghphhm
rkndcwngesftgkladqaskanlmfeggknmtpvytgalkdelvktdkiygkikkrllw
gsdlatmircarafgglmdelkahcvtlpirvgmnmnedgpiiferhsrykyhydadysr
wdstqqravlaaaleimvkfssephlaqvvaedllspsvvdvgdfkisineglpsgvpct
sqwnsiahwlltlcalsevtnlspdiiqanslfsfygddeivstdikldpekltaklkey
glkptrpdktegplvisedlngltflrrtvtrdpagwfgkleqssilrqmywtrgpnhed
psetmiphsqrpiqlmsllgeaalhgpafyskisklviaelkeggmdfyvprqepmfrwm
rfsdlstwegdrnlapsfvn