PDB entry 4nf8

View 4nf8 on RCSB PDB site
Description: Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and glutamate in PEG2000MME
Class: transport protein, receptor
Keywords: receptor, glycine and glutamate, transport protein
Deposited on 2013-10-30, released 2014-03-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-08-09, with a file datestamp of 2017-08-04.
Experiment type: XRAY
Resolution: 1.86 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor ionotropic, NMDA 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Grin1, Nmdar1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35439 (Start-151)
    • Uniprot P35439 (154-End)
      • expression tag (152-153)
    Domains in SCOPe 2.07: d4nf8a_
  • Chain 'B':
    Compound: Glutamate receptor ionotropic, NMDA 2A
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Grin2a
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q00959 (1-138)
    • Uniprot Q00959 (141-End)
      • engineered mutation (238)
    Domains in SCOPe 2.07: d4nf8b_
  • Heterogens: GLY, GLU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4nf8A (A:)
gmstrlkivtihqepfvyvkptmsdgtckeeftvngdpvkkvictgpndtspgsprhtvp
qccygfcidlliklartmnftyevhlvadgkfgtqervnnsnkkewngmmgellsgqadm
ivapltinneraqyiefskpfkyqgltilvkkgtritgindprlrnpsdkfiyatvkqss
vdiyfrrqvelstmyrhmekhnyesaaeaiqavrdnklhafiwdsavlefeasqkcdlvt
tgelffrsgfgigmrkdspwkqnvslsilkshengfmedldktwvryqecds

    Sequence, based on observed residues (ATOM records): (download) 
    >4nf8A (A:)
strlkivtihqepfvyvkptmsdgtckeeftvngdpvkkvictgpndtspgsprhtvpqc
cygfcidlliklartmnftyevhlvadgkfgtqervsnkkewngmmgellsgqadmivap
ltinneraqyiefskpfkyqgltilvkkgtritgindprlrnpsdkfiyatvkqssvdiy
frrqvelstmyrhmekhnyesaaeaiqavrdnklhafiwdsavlefeasqkcdlvttgel
ffrsgfgigmrkdspwkqnvslsilkshengfmedldktwvryqe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4nf8B (B:)
sddnhlsivtleeapfvivedidpltetcvrntvpcrkfvkinnstnegmnvkkcckgfc
idilkklsrtvkftydlylvtngkhgkkvnnvwngmigevvyqravmavgsltineerse
vvdfsvpfvetgisvmvsrgtqvtglsdkkfqrphdysppfrfgtvpngsternirnnyp
ymhqymtrfnqrgvedalvslktgkldafiydaavlnykagrdegcklvtigsgyifatt
gygialqkgspwkrqidlallqfvgdgemeeletlwltgichn

    Sequence, based on observed residues (ATOM records): (download) 
    >4nf8B (B:)
ddnhlsivtleeapfvivedidpltetcvrntvpcrkfvkinnstnegmnvkkcckgfci
dilkklsrtvkftydlylvtngkhgkkvnnvwngmigevvyqravmavgsltineersev
vdfsvpfvetgisvmvsrgtqvtglsdkkfqrphdysppfrfgtvpngsternirnnypy
mhqymtrfnqrgvedalvslktgkldafiydaavlnykagrdegcklvtigsgyifattg
ygialqkgspwkrqidlallqfvgdgemeeletlwltgic