PDB entry 4jzb
View 4jzb on RCSB PDB site
Description: Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)-3-PHENYLPYRIDINIUM, IPP and Ca2+
Class: transferase/transferase inhibitor
Keywords: Geranyl Transferase, FPPS, farnesyl pyrophosphate synthase, farnesyl diphosphate synthase, cytosolic, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on
2013-04-02, released
2014-02-12
The last revision prior to the SCOPe 2.07 freeze date was dated
2017-11-15, with a file datestamp of
2017-11-10.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: farnesyl pyrophosphate synthase
Species: Leishmania major [TaxId:5664]
Gene: FPPS, LMJF_22_1360
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d4jzba1, d4jzba2 - Chain 'B':
Compound: farnesyl pyrophosphate synthase
Species: Leishmania major [TaxId:5664]
Gene: FPPS, LMJF_22_1360
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d4jzbb1, d4jzbb2 - Heterogens: CA, IPE, P2H, NA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4jzbA (A:)
mahmerfqkvyeevqefllgdaekrfemdvhrkgylksmmdttclggkynrglcvvdvae
amakdtqmdaaamervlhdacvcgwmiemlqahflveddimdhsktrrgkpcwylhpgvt
aqvaindglillawatqmalhyfadrpflaevlrvfhdvdltttigqlydvtsmvdsakl
dakvahanttdyveytpfnhrrivvyktayytywlplvmgllvsgtlekvdkkathkvam
vmgeyfqvqddvmdcftppeklgkigtdiedakcswlavtflttapaekvaefkanygst
dpaavavikqlyteqnllarfeeyekavvaeveqliaaleaqnaafaasvkvlwsktykr
qk
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4jzbB (B:)
mahmerfqkvyeevqefllgdaekrfemdvhrkgylksmmdttclggkynrglcvvdvae
amakdtqmdaaamervlhdacvcgwmiemlqahflveddimdhsktrrgkpcwylhpgvt
aqvaindglillawatqmalhyfadrpflaevlrvfhdvdltttigqlydvtsmvdsakl
dakvahanttdyveytpfnhrrivvyktayytywlplvmgllvsgtlekvdkkathkvam
vmgeyfqvqddvmdcftppeklgkigtdiedakcswlavtflttapaekvaefkanygst
dpaavavikqlyteqnllarfeeyekavvaeveqliaaleaqnaafaasvkvlwsktykr
qk