PDB entry 4jvn

View 4jvn on RCSB PDB site
Description: Crystal structure of human estrogen sulfotransferase (SULT1E1) in complex with inactive cofactor PAP and metabolite of brominated flame retardant 3OH BDE47 (3-hydroxyl bromodiphenyl ether)
Class: transferase
Keywords: sulfotransferase, TRANSFERASE
Deposited on 2013-03-25, released 2013-09-04
The last revision prior to the SCOPe 2.04 freeze date was dated 2013-10-16, with a file datestamp of 2013-10-11.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.187
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: estrogen sulfotransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: STE, SULT1E1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49888
      • engineered mutation (268)
    Domains in SCOPe 2.04: d4jvna_
  • Chain 'B':
    Compound: estrogen sulfotransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: STE, SULT1E1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49888
      • engineered mutation (268)
    Domains in SCOPe 2.04: d4jvnb_
  • Heterogens: YUG, A3P, NA, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4jvnA (A:)
mnseldyyekfeevhgilmykdfvkywdnveafqarpddlviatypksgttwvseivymi
ykegdvekckedvifnripflecrkenlmngvkqldemnsprivkthlppellpasfwek
dckiiylcrnakdvavsfyyfflmvaghpnpgsfpefvekfmqgqvpygswykhvkswwe
kgksprvlflfyedlkedirkeviklihflerkpseelvdriihhtsfqemknnpstnyt
tlpdeimnqklspfmrkgitgdwknhftealnekfdkhyeqqmkestlkfrtei

    Sequence, based on observed residues (ATOM records): (download) 
    >4jvnA (A:)
seldyyekfeevhgilmykdfvkywdnveafqarpddlviatypksgttwvseivymiyk
egdvekckedvifnripflecrkenlmngvkqldemnsprivkthlppellpasfwekdc
kiiylcrnakdvavsfyyfflmvaghpnpgsfpefvekfmqgqvpygswykhvkswwekg
ksprvlflfyedlkedirkeviklihflerkpseelvdriihhtsfqemknnpstnyttl
pdeimnqklspfmrkgitgdwknhftealnekfdkhyeqqmkestlkfrte

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4jvnB (B:)
mnseldyyekfeevhgilmykdfvkywdnveafqarpddlviatypksgttwvseivymi
ykegdvekckedvifnripflecrkenlmngvkqldemnsprivkthlppellpasfwek
dckiiylcrnakdvavsfyyfflmvaghpnpgsfpefvekfmqgqvpygswykhvkswwe
kgksprvlflfyedlkedirkeviklihflerkpseelvdriihhtsfqemknnpstnyt
tlpdeimnqklspfmrkgitgdwknhftealnekfdkhyeqqmkestlkfrtei

    Sequence, based on observed residues (ATOM records): (download) 
    >4jvnB (B:)
seldyyekfeevhgilmykdfvkywdnveafqarpddlviatypksgttwvseivymiyk
egdvekckedvifnripflecrkenlmngvkqldemnsprivkthlppellpasfwekdc
kiiylcrnakdvavsfyyfflmvaghpnpgsfpefvekfmqgqvpygswykhvkswwekg
ksprvlflfyedlkedirkeviklihflerkpseelvdriihhtsfqemknnpstnyttl
pdeimnqklspfmrkgitgdwknhftealnekfdkhyeqqmkestlkfrte