PDB entry 4ju1

View 4ju1 on RCSB PDB site
Description: Crystal structure of hcv ns5b polymerase in complex with compound 6
Class: transferase/transferase inhibitor
Keywords: RNA-directed RNA polymerase, transferase, transferase-transferase inhibitor complex
Deposited on 2013-03-24, released 2013-07-03
The last revision prior to the SCOPe 2.04 freeze date was dated 2014-03-26, with a file datestamp of 2014-03-21.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.195
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Genome polyprotein
    Species: Hepatitis C virus [TaxId:420174]
    Gene: NS5B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4ju1a_
  • Chain 'B':
    Compound: Genome polyprotein
    Species: Hepatitis C virus [TaxId:420174]
    Gene: NS5B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4ju1b_
  • Heterogens: GOL, 1NZ, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ju1A (A:)
smsytwtgalitpcaaeesklpinplsnsllrhhnmvyattsrsaslrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsieeackltpphsakskfgygakdvrnlssravnhir
svwedlledtetpidttimaksevfcvqpekggrkparlivfpdlgvrvcekmalydvvs
tlpqavmgssygfqyspkqrveflvntwkskkcpmgfsydtrcfdstvtesdirveesiy
qccdlapearqairslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkat
aacraaklqdctmlvngddlvvicesagtqedaaalrafteamtrysappgdppqpeydl
elitscssnvsvahdasgkrvyyltrdpttplaraawetarhtpinswlgniimyaptlw
armilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsaftlhsyspg
einrvasclrklgvpplrtwrhrarsvrakllsqggraatcgrylfnwavrtklkltpip
aasqldlsgwfvagysggdiyhslsrarprhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4ju1A (A:)
smsytwtgalitpcaaeesklpinplsnsllrhhnmvyattsrsaslrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsieeackltpphsakskfgygakdvrnlssravnhir
svwedlledtetpidttimaksevfcvqpgrkparlivfpdlgvrvcekmalydvvstlp
qavmgssygfqyspkqrveflvntwkskkcpmgfsydtrcfdstvtesdirveesiyqcc
dlapearqairslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkataac
raaklqdctmlvngddlvvicesagtqedaaalrafteamtrysappgdppqpeydleli
tscssnvsvahdasgkrvyyltrdpttplaraawetarhtpinswlgniimyaptlwarm
ilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsaftlhsyspgein
rvasclrklgvpplrtwrhrarsvrakllsqggraatcgrylfnwavrtklkltpipaas
qldlsgwfvagysggdiyhs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ju1B (B:)
smsytwtgalitpcaaeesklpinplsnsllrhhnmvyattsrsaslrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsieeackltpphsakskfgygakdvrnlssravnhir
svwedlledtetpidttimaksevfcvqpekggrkparlivfpdlgvrvcekmalydvvs
tlpqavmgssygfqyspkqrveflvntwkskkcpmgfsydtrcfdstvtesdirveesiy
qccdlapearqairslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkat
aacraaklqdctmlvngddlvvicesagtqedaaalrafteamtrysappgdppqpeydl
elitscssnvsvahdasgkrvyyltrdpttplaraawetarhtpinswlgniimyaptlw
armilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsaftlhsyspg
einrvasclrklgvpplrtwrhrarsvrakllsqggraatcgrylfnwavrtklkltpip
aasqldlsgwfvagysggdiyhslsrarprhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4ju1B (B:)
smsytwtgalitpcaaeesklpinplsnsllrhhnmvyattsrsaslrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsieeackltpphsakskfgygakdvrnlssravnhir
svwedlledtetpidttimaksevfcvqpgrkparlivfpdlgvrvcekmalydvvstlp
qavmgssygfqyspkqrveflvntwkskkcpmgfsydtrcfdstvtesdirveesiyqcc
dlapearqairslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkataac
raaklqdctmlvngddlvvicesagtqedaaalrafteamtrysappgdppqpeydleli
tscssnvsvahdasgkrvyyltrdpttplaraawetarhtpinswlgniimyaptlwarm
ilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsaftlhsyspgein
rvasclrklgvpplrtwrhrarsvrakllsqggraatcgrylfnwavrtklkltpipaas
qldlsgwfvagysggdiyhs