PDB entry 4is2

View 4is2 on RCSB PDB site
Description: Crystal structure of the apo form of a 3alpha-hydroxysteroid dehydrogenase (BaiA2) associated with secondary bile acid synthesis from Clostridium scindens VPI12708 at 1.90 A resolution
Class: oxidoreductase
Keywords: NAD(P)-binding Rossmann-fold domains, Structural Genomics, Joint Center for Structural Genomics, JCSG, Protein Structure Initiative, PSI-BIOLOGY, OXIDOREDUCTASE
Deposited on 2013-01-16, released 2013-04-03
The last revision prior to the SCOPe 2.04 freeze date was dated 2013-09-04, with a file datestamp of 2013-08-30.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.163
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bile acid 3-alpha hydroxysteroid dehydrogenase
    Species: Clostridium scindens [TaxId:29347]
    Gene: baiA, BAIA2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4is2a_
  • Heterogens: CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4is2A (A:)
mgsdkihhhhhhenlyfqgmnlvqdkvtiitggtrgigfaaakifidngakvsifgetqe
evdtalaqlkelypeeevlgfapdltsrdavmaavgqvaqkygrldvminnagitsnnvf
srvseeefkhimdinvtgvfngawcayqcmkdakkgviintasvtgifgslsgvgypask
asviglthglgreiirknirvvgvapgvvntdmtngnppeimegylkalpmkrmlepeei
anvylflasdlasgitattvsvdgayrp

    Sequence, based on observed residues (ATOM records): (download) 
    >4is2A (A:)
mnlvqdkvtiitggtrgigfaaakifidngakvsifgetqeevdtalaqlkelypeeevl
gfapdltsrdavmaavgqvaqkygrldvminnagitsnnvfsrvseeefkhimdinvtgv
fngawcayqcmkdakkgviintasvtgifpaskasviglthglgreiirknirvvgvapg
vvntmlepeeianvylflasdlasgitattvsvdg