PDB entry 4h9x

View 4h9x on RCSB PDB site
Description: Structure of Geobacillus kaustophilus lactonase, mutant E101G/R230C/D266N with Zn2+ and bound N-butyryl-DL-homoserine lactone
Class: hydrolase
Keywords: (beta/alpha)8 barrel, HYDROLASE
Deposited on 2012-09-25, released 2012-11-07
The last revision prior to the SCOPe 2.03 freeze date was dated 2013-05-22, with a file datestamp of 2013-05-17.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.178
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phosphotriesterase
    Species: Geobacillus kaustophilus [TaxId:235909]
    Gene: GK1506
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5KZU5
      • engineered mutation (233)
      • engineered mutation (269)
    Domains in SCOPe 2.03: d4h9xa_
  • Chain 'B':
    Compound: phosphotriesterase
    Species: Geobacillus kaustophilus [TaxId:235909]
    Gene: GK1506
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5KZU5
      • engineered mutation (233)
      • engineered mutation (269)
    Domains in SCOPe 2.03: d4h9xb_
  • Heterogens: FE, ZN, OH, HL4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4h9xA (A:)
gshnmaemvetvcgpvpveqlgktlihehflfgypgfqgdvtrgtfredeslrvaveaae
kmkrhgiqtvvdptpndcgrnpaflrrvaeetglniicatgyyyggegappyfqfrrllg
taeddiydmfmaeltegiadtgikagviklasskgriteyekmffraaaraqketgavii
thtqegtmgpeqaayllehgadpkkivighmcgntdpdyhrktlaygvyiafdcfgiqgm
vgaptdeervrtllallrdgyekqimlshntvnvwlgrpftlpepfaemmknwhvehlfv
niipalknegirdevleqmfignpaalfsa

    Sequence, based on observed residues (ATOM records): (download) 
    >4h9xA (A:)
emvetvcgpvpveqlgktlihehflfgypgfqgdvtrgtfredeslrvaveaaekmkrhg
iqtvvdptpndcgrnpaflrrvaeetglniicatgyyyppyfqfrrllgtaeddiydmfm
aeltegiadtgikagviklasskgriteyekmffraaaraqketgaviithtqegtmgpe
qaayllehgadpkkivighmcgntdpdyhrktlaygvyiafdcfgiqgmvgaptdeervr
tllallrdgyekqimlshntvnvwlgrpftlpepfaemmknwhvehlfvniipalknegi
rdevleqmfignpaalfs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4h9xB (B:)
gshnmaemvetvcgpvpveqlgktlihehflfgypgfqgdvtrgtfredeslrvaveaae
kmkrhgiqtvvdptpndcgrnpaflrrvaeetglniicatgyyyggegappyfqfrrllg
taeddiydmfmaeltegiadtgikagviklasskgriteyekmffraaaraqketgavii
thtqegtmgpeqaayllehgadpkkivighmcgntdpdyhrktlaygvyiafdcfgiqgm
vgaptdeervrtllallrdgyekqimlshntvnvwlgrpftlpepfaemmknwhvehlfv
niipalknegirdevleqmfignpaalfsa

    Sequence, based on observed residues (ATOM records): (download) 
    >4h9xB (B:)
emvetvcgpvpveqlgktlihehflfgypgfqgdvtrgtfredeslrvaveaaekmkrhg
iqtvvdptpndcgrnpaflrrvaeetglniicatgyyyppyfqfrrllgtaeddiydmfm
aeltegiadtgikagviklasskgriteyekmffraaaraqketgaviithtqegtmgpe
qaayllehgadpkkivighmcgntdpdyhrktlaygvyiafdcfgiqgmvgaptdeervr
tllallrdgyekqimlshntvnvwlgrpftlpepfaemmknwhvehlfvniipalknegi
rdevleqmfignpaalfs