PDB entry 4grt

View 4grt on RCSB PDB site
Description: human glutathione reductase a34e, r37w mutant, mixed disulfide between trypanothione and the enzyme
Class: oxidoreductase
Keywords: oxidoreductase, flavoenzyme, mixed disulfide
Deposited on 1997-02-12, released 1997-08-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.189
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glutathione reductase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00390 (0-460)
      • engineered (16)
      • engineered (19)
    Domains in SCOPe 2.07: d4grta1, d4grta2, d4grta3
  • Heterogens: FAD, GCG

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4grtA (A:)
vasydylvigggsgglesawraaelgaraavveshklggtcvnvgcvpkkvmwntavhse
fmhdhadygfpscegkfnwrvikekrdayvsrlnaiyqnnltkshieiirghaaftsdpk
ptievsgkkytaphiliatggmpstphesqipgaslgitsdgffqleelpgrsvivgagy
iavemagilsalgsktslmirhdkvlrsfdsmistncteelenagvevlkfsqvkevkkt
lsglevsmvtavpgrlpvmtmipdvdcllwaigrvpntkdlslnklgiqtddkghiivde
fqntnvkgiyavgdvcgkalltpvaiaagrklahrlfeykedskldynniptvvfshppi
gtvgltedeaihkygienvktystsftpmyhavtkrktkcvmkmvcankeekvvgihmqg
lgcdemlqgfavavkmgatkadfdntvaihptsseelvtlr