PDB entry 4d6i

View 4d6i on RCSB PDB site
Description: Crystal structure of a family 98 glycoside hydrolase catalytic module (Sp3GH98) in complex with the type 1 blood group A-tetrasaccharide (E558A L19 mutant)
Class: hydrolase
Keywords: hydrolase, blood group antigen
Deposited on 2014-11-11, released 2014-11-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-07-05, with a file datestamp of 2017-06-30.
Experiment type: XRAY
Resolution: 1.99 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glycoside hydrolase
    Species: STREPTOCOCCUS PNEUMONIAE [TaxId:406556]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A5LBQ0 (0-582)
      • engineered mutation (109)
      • engineered mutation (137-138)
      • engineered mutation (171)
      • expression tag (583-586)
    Domains in SCOPe 2.07: d4d6ia1, d4d6ia2, d4d6ia3
  • Heterogens: FUC, GAL, NAG, A2G, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4d6iA (A:)
evdkrreinnehpllmmplyangeefnqgkytfwggdtltgkwenipddlkpytviqlhp
ddlpkrdgaardfyehmleeaakyvnpktgknepipviltvytagnmpyhtsahwlstsw
idkmyqkypnlhgifstasywiwandienkaadylkvsaknggyfiwaeqnsgsaiekaf
gkngkiafqksvdkywknlifmfkntpaaegndsttesymkglwlsnhtyqwgglmdtwk
wyetgkwklfasgnigksqgdrqwltepesmlgeealgvylnggvvynfehpaytygvnn
kesllfsevikeffryviahpapskekvledtkvfihgdysnkgngkffvnvntdreqtp
lymtgrynvipaipgvlktdklkesvsssriqikeitspefsstqarkeylnklypmnye
gdifaqkldnrwfvynykvnenvkqtgklkfnslemnvefephtygiferisnglkvnln
nfrtnkdslwsnaqdanqakklpqltkkgaikwieehyikdtqfgekrvtkivlrgidkl
ptihslsgtnnsydqpslnfdqknhmvtitinsngnlefelhflehtrappppplrsgc

    Sequence, based on observed residues (ATOM records): (download) 
    >4d6iA (A:)
evdkrreinnehpllmmplyangeefnqgkytfwggdtltgkwenipddlkpytviqlhp
ddlpkrdgaardfyehmleeaakyvnpktgknepipviltvytagnmpyhtsahwlstsw
idkmyqkypnlhgifstasywiwandienkaadylkvsaknggyfiwaeqnsgsaiekaf
gkngkiafqksvdkywknlifmfkntpaaegndsttesymkglwlsnhtyqwgglmdtwk
wyetgkwklfasgnigksqgdrqwltepesmlgeealgvylnggvvynfehpaytygvnn
kesllfsevikeffryviahpapskekvledtkvfihgdysnkgngkffvnvntdreqtp
lymtgrynvipaipgvlktdklkesvsssriqikeitspefsstqarkeylnklypmnye
gdifaqkldnrwfvynykvnenvkqtgklkfnslemnvefephtygiferisnglkvnln
nfrtnkdslwsnaqdanqakklpqltkkgaikwieehyikdtqfgekrvtkivlrgidkl
ptihslsgtnnsydqpslnfdqknhmvtitinsngnlefelhfleht