PDB entry 4c4n

View 4c4n on RCSB PDB site
Description: Crystal structure of the Sonic Hedgehog-heparin complex
Class: signaling protein
Keywords: signaling protein, hedgehog signalling, morphogens, heparan sulphate proteoglycans, glycosaminoglycans
Deposited on 2013-09-05, released 2013-10-02
The last revision prior to the SCOPe 2.04 freeze date was dated 2013-10-30, with a file datestamp of 2013-10-25.
Experiment type: XRAY
Resolution: 2.36 Å
R-factor: 0.20225
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Sonic hedgehog protein
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4c4na_
  • Chain 'B':
    Compound: Sonic hedgehog protein
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4c4nb_
  • Heterogens: ZN, CA, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4c4nA (A:)
maltplaykqfipnvaektlgasgryegkitrnserfkeltpnynpdiifkdeentgadr
lmtqrckdklnalaisvmnqwpgvklrvtegwdedghhseeslhyegravdittsdrdrs
kygmlarlaveagfdwvyyeskahihcsvkaensvaakhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4c4nA (A:)
ltplaykqfipnvaektlgasgryegkitrnserfkeltpnynpdiifkdeentgadrlm
tqrckdklnalaisvmnqwpgvklrvtegwdedghhseeslhyegravdittsdrdrsky
gmlarlaveagfdwvyyeskahihcsvkaen

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4c4nB (B:)
maltplaykqfipnvaektlgasgryegkitrnserfkeltpnynpdiifkdeentgadr
lmtqrckdklnalaisvmnqwpgvklrvtegwdedghhseeslhyegravdittsdrdrs
kygmlarlaveagfdwvyyeskahihcsvkaensvaakhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4c4nB (B:)
ltplaykqfipnvaektlgasgryegkitrnserfkeltpnynpdiifkdeentgadrlm
tqrckdklnalaisvmnqwpgvklrvtegwdedghhseeslhyegravdittsdrdrsky
gmlarlaveagfdwvyyeskahihcsvkaens