PDB entry 4bo8

View 4bo8 on RCSB PDB site
Description: Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 1-(2-amino-4- phenylimidazol-1-yl)-3-(2-fluorophenyl)urea at 2.7A resolution
Class: oxidoreductase
Keywords: oxidoreductase, rossmann fold, fatty acid biosynthesis
Deposited on 2013-05-18, released 2013-09-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-11-27, with a file datestamp of 2013-11-22.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.25454
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54438 (22-268)
      • expression tag (20-21)
    Domains in SCOPe 2.07: d4bo8a1, d4bo8a2
  • Chain 'B':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54438 (22-268)
      • expression tag (21)
    Domains in SCOPe 2.07: d4bo8b1, d4bo8b2
  • Chain 'C':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54438 (22-268)
      • expression tag (5-7)
      • expression tag (16-21)
    Domains in SCOPe 2.07: d4bo8c1, d4bo8c2
  • Chain 'D':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54438 (22-268)
      • expression tag (17-21)
    Domains in SCOPe 2.07: d4bo8d1, d4bo8d2
  • Heterogens: 34X, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4bo8A (A:)
mhhhhhhssgvdlgtenlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtats
asgaekiaetlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnll
vrmkddewfdvvntnlnslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaak
aglegftralarevgsraitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeei
akvvgflasdgaayvtgatvpvnggmyms

    Sequence, based on observed residues (ATOM records): (download) 
    >4bo8A (A:)
qsmslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlkangvegag
lvldvssdesvaatlehiqqhlgqplivvnnagewfdvvntnlnslyrlskavlrgmtka
rwgriinigsvvgamgnagqtnyaaakaglegftralarevgsraitvnavapgfidtdm
trelpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpvnggmyms

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4bo8B (B:)
mhhhhhhssgvdlgtenlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtats
asgaekiaetlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnll
vrmkddewfdvvntnlnslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaak
aglegftralarevgsraitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeei
akvvgflasdgaayvtgatvpvnggmyms

    Sequence, based on observed residues (ATOM records): (download) 
    >4bo8B (B:)
smslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlkangvegagl
vldvssdesvaatlehiqqhlgqplivvnnagidewfdvvntnlnslyrlskavlrgmtk
arwgriinigsvagqtnyaaakaglegftralarevgsraitvnavapgfidtdmtrelp
eaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpvnggmyms

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4bo8C (C:)
mhhhhhhssgvdlgtenlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtats
asgaekiaetlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnll
vrmkddewfdvvntnlnslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaak
aglegftralarevgsraitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeei
akvvgflasdgaayvtgatvpvnggmyms

    Sequence, based on observed residues (ATOM records): (download) 
    >4bo8C (C:)
hhsnlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlka
ngvegaglvldvssdesvaatlehiqqhlgqplivvnnagdewfdvvntnlnslyrlska
vlrgmtkarwgriinigsvvgagqtnyaaakaglegftralarevgsraitvnavapgfi
dtdmtrelpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpvnggmyms

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4bo8D (D:)
mhhhhhhssgvdlgtenlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtats
asgaekiaetlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnll
vrmkddewfdvvntnlnslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaak
aglegftralarevgsraitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeei
akvvgflasdgaayvtgatvpvnggmyms

    Sequence, based on observed residues (ATOM records): (download) 
    >4bo8D (D:)
lyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlkangve
gaglvldvssdesvaatlehiqqhlgqplivvnnagirmkddewfdvvntnlnslyrlsk
avlrgmtkarwgriinigsvvgamgnagqtnyaaakaglegftralarevgsraitvnav
apgfidtdmtrelpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpvng
gmyms