PDB entry 3vqe

View 3vqe on RCSB PDB site
Description: HIV-1 IN core domain in complex with [1-(4-fluorophenyl)-5-methyl-1H-pyrazol-4-yl]methanol
Class: transferase/transferase inhibitor
Keywords: RNAseH, DNA binding, DNA cleavage, DNA integration, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2012-03-21, released 2013-01-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-01-30, with a file datestamp of 2013-01-25.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.2
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pol polyprotein
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q72498
      • engineered mutation (67-68)
      • engineered mutation (71)
      • engineered mutation (75)
      • engineered mutation (129)
    Domains in SCOPe 2.07: d3vqea_
  • Chain 'B':
    Compound: Pol polyprotein
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q72498
      • engineered mutation (67-68)
      • engineered mutation (71)
      • engineered mutation (75)
      • engineered mutation (129)
    Domains in SCOPe 2.07: d3vqeb_
  • Heterogens: CD, CL, SO4, FMQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3vqeA (A:)
sspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftgatvraacdwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlkta
vqmavfihnhkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >3vqeA (A:)
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftgatvraacdwagikqesmnkelkkiigqvrdqaehlktavqmavfihnhkrkgg
ysagerivdiiatdiq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3vqeB (B:)
sspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftgatvraacdwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlkta
vqmavfihnhkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >3vqeB (B:)
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftgatvraacdwagikqesmnkelkkiigqvrdqaehlktavqmavfihnhkrgys
agerivdiiatdi