PDB entry 3vq9

View 3vq9 on RCSB PDB site
Description: HIV-1 IN core domain in complex with 6-fluoro-1,3-benzothiazol-2-amine
Class: transferase/transferase inhibitor
Keywords: RNaseH, DNA binding, DNA cleavage, DNA integration, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2012-03-20, released 2013-01-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-01-30, with a file datestamp of 2013-01-25.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.198
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pol polyprotein
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q72498
      • engineered mutation (135)
    Domains in SCOPe 2.07: d3vq9a_
  • Chain 'B':
    Compound: Pol polyprotein
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q72498 (Start-160)
      • engineered mutation (135)
    Domains in SCOPe 2.07: d3vq9b_
  • Chain 'C':
    Compound: Pol polyprotein
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q72498 (0-160)
      • engineered mutation (135)
    Domains in SCOPe 2.07: d3vq9c_
  • Heterogens: FBB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3vq9A (A:)
mhgqvdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwp
vktvhtdngsnftsttvkaacwwagikqefgipynpqsqgviesmnkelkkiigqvrdqa
ehlktavqmavfihnhkrkggiggysagerivdiiatdiqt

    Sequence, based on observed residues (ATOM records): (download) 
    >3vq9A (A:)
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsttvkaacwwagikqefgiesmnkelkkiigqvrdqaehlktavqmavfihnhk
rkggiggysagerivdiiatdi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3vq9B (B:)
mhgqvdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwp
vktvhtdngsnftsttvkaacwwagikqefgipynpqsqgviesmnkelkkiigqvrdqa
ehlktavqmavfihnhkrkggiggysagerivdiiatdiqt

    Sequence, based on observed residues (ATOM records): (download) 
    >3vq9B (B:)
cspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsttvkaacwwagikqefviesmnkelkkiigqvrdqaehlktavqmavfihnh
krkggysagerivdiiatdiqt

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3vq9C (C:)
mhgqvdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwp
vktvhtdngsnftsttvkaacwwagikqefgipynpqsqgviesmnkelkkiigqvrdqa
ehlktavqmavfihnhkrkggiggysagerivdiiatdiqt

    Sequence, based on observed residues (ATOM records): (download) 
    >3vq9C (C:)
mhgqvdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwp
vktvhtdngsnftsttvkaacwwagikqefgipynpqsqgviesmnkelkkiigqvrdqa
ehlktavqmavfihnhkrkggysagerivdiiatdiqt