PDB entry 3vq7

View 3vq7 on RCSB PDB site
Description: HIV-1 IN core domain in complex with 4-(1H-pyrrol-1-yl)aniline
Class: transferase/transferase inhibitor
Keywords: RNaseH, DNA binding, DNA cleavage, DNA integration, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2012-03-20, released 2013-01-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-01-30, with a file datestamp of 2013-01-25.
Experiment type: XRAY
Resolution: 1.63 Å
R-factor: 0.2
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pol polyprotein
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q72498
      • engineered mutation (76)
      • engineered mutation (84)
      • engineered mutation (130)
    Domains in SCOPe 2.07: d3vq7a_
  • Chain 'B':
    Compound: Pol polyprotein
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q72498
      • engineered mutation (1)
      • engineered mutation (76)
      • engineered mutation (84)
      • engineered mutation (130)
    Domains in SCOPe 2.07: d3vq7b_
  • Heterogens: CD, SO4, SNU, SUC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3vq7A (A:)
dsspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvh
tdngsnftsttvkaacdwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlkt
avqmavfihnhkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >3vq7A (A:)
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsttvkaacdwagikqedgipyviesmnkelkkiigqvrdqaehlktavqmavfi
hnhkrkggiggysagerivdiiatd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3vq7B (B:)
dsspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvh
tdngsnftsttvkaacdwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlkt
avqmavfihnhkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >3vq7B (B:)
sspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsttvkaacdwagikqedsmnkelkkiigqvrdqaehlktavqmavfihnhkrk
ggiggysagerivdiiatdiq