PDB entry 3v3q

View 3v3q on RCSB PDB site
Description: Crystal Structure of Human Nur77 Ligand-binding Domain in Complex with Ethyl 2-[2,3,4 trimethoxy-6(1-octanoyl)phenyl]acetate
Class: TRANSCRIPTION/antagonist
Keywords: orphan nuclear receptor, protein-antagonist complex, TRANSCRIPTION, TRANSCRIPTION-antagonist complex
Deposited on 2011-12-14, released 2012-09-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-07-10, with a file datestamp of 2013-07-05.
Experiment type: XRAY
Resolution: 2.22 Å
R-factor: 0.213
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nuclear receptor subfamily 4 group A member 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NR4A1, GFRP1, HMR, NAK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22736 (Start-248)
      • expression tag (249)
    Domains in SCOPe 2.07: d3v3qa1, d3v3qa2
  • Chain 'B':
    Compound: Nuclear receptor subfamily 4 group A member 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NR4A1, GFRP1, HMR, NAK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22736 (Start-248)
      • expression tag (250)
    Domains in SCOPe 2.07: d3v3qb1, d3v3qb2
  • Heterogens: TMY, GOL, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3v3qA (A:)
mskpkqppdaspanlltslvrahldsgpstakldyskfqelvlphfgkedagdvqqfydl
lsgslevirkwaekipgfaelspadqdlllesaflelfilrlayrskpgegklifcsglv
lhrlqcargfgdwidsilafsrslhsllvdvpafaclsalvlitdrhglqeprrveelqn
riasclkehvaavagepqpasclsrllgklpelrtlctqglqrifylkledlvppppiid
kifmdtlpflehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3v3qA (A:)
dapanlltslvrahldsgpstakldyskfqelvlphfgkedagdvqqfydllsgslevir
kwaekipgfaelspadqdlllesaflelfilrlayrskpgegklifcsglvlhrlqcarg
fgdwidsilafsrslhsllvdvpafaclsalvlitdrhglqeprrveelqnriasclkeh
vaavapasclsrllgklpelrtlctqglqrifylkledlvppppiidkifmdtlpfl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3v3qB (B:)
mskpkqppdaspanlltslvrahldsgpstakldyskfqelvlphfgkedagdvqqfydl
lsgslevirkwaekipgfaelspadqdlllesaflelfilrlayrskpgegklifcsglv
lhrlqcargfgdwidsilafsrslhsllvdvpafaclsalvlitdrhglqeprrveelqn
riasclkehvaavagepqpasclsrllgklpelrtlctqglqrifylkledlvppppiid
kifmdtlpflehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3v3qB (B:)
panlltslvrahldsgpstakldyskfqelvlphfgkedagdvqqfydllsgslevirkw
aekipgfaelspadqdlllesaflelfilrlayrskpgegklifcsglvlhrlqcargfg
dwidsilafsrslhsllvdvpafaclsalvlitdrhglqeprrveelqnriasclkehva
avagepqpasclsrllgklpelrtlctqglqrifylkledlvppppiidkifmdtlpfe