PDB entry 3rlu

View 3rlu on RCSB PDB site
Description: Crystal structure of the mutant K82A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
Class: lyase/lyase inhibitor
Keywords: tim barrel fold, LYASE-LYASE INHIBITOR complex
Deposited on 2011-04-20, released 2012-04-25
The last revision prior to the SCOPe 2.03 freeze date was dated 2013-06-19, with a file datestamp of 2013-06-14.
Experiment type: XRAY
Resolution: 1.49 Å
R-factor: 0.154
AEROSPACI score: 0.67 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: orotidine 5'-phosphate decarboxylase
    Species: METHANOTHERMOBACTER THERMAUTOTROPHICUS [TaxId:187420]
    Gene: pyrF, MTH_129
    Database cross-references and differences (RAF-indexed):
    • Uniprot O26232
      • engineered mutation (81)
      • engineered mutation (100)
    Domains in SCOPe 2.03: d3rlua_
  • Chain 'B':
    Compound: orotidine 5'-phosphate decarboxylase
    Species: METHANOTHERMOBACTER THERMAUTOTROPHICUS [TaxId:187420]
    Gene: pyrF, MTH_129
    Database cross-references and differences (RAF-indexed):
    • Uniprot O26232
      • engineered mutation (81)
      • engineered mutation (100)
    Domains in SCOPe 2.03: d3rlub_
  • Heterogens: BMP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3rluA (A:)
mrsrrvdvmdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefr
krfgcriiadfkvadipetneaicratfkagadaiivhgfpgadsvraclnvaeemgrev
flltemshpgaemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsflisp
gvgaqggdpgetlrfadaiivgrsiyladnpaaaaagiiesikdllnp

    Sequence, based on observed residues (ATOM records): (download) 
    >3rluA (A:)
dvmdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefrkrfgcr
iiadfkvadipetneaicratfkagadaiivhgfpgadsvraclnvaeemgrevflltem
shpgaemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsflispgvgaqg
gdpgetlrfadaiivgrsiyladnpaaaaagiiesikdll

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3rluB (B:)
mrsrrvdvmdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefr
krfgcriiadfkvadipetneaicratfkagadaiivhgfpgadsvraclnvaeemgrev
flltemshpgaemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsflisp
gvgaqggdpgetlrfadaiivgrsiyladnpaaaaagiiesikdllnp

    Sequence, based on observed residues (ATOM records): (download) 
    >3rluB (B:)
mdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefrkrfgcrii
adfkvadipetneaicratfkagadaiivhgfpgadsvraclnvaeemgrevflltemsh
pgaemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsflispgvgaqggd
pgetlrfadaiivgrsiyladnpaaaaagiiesikdll