PDB entry 3n9s

View 3n9s on RCSB PDB site
Description: Class II fructose-1,6-bisphosphate aldolase from helicobacter pylori in complex with N-(4-hydroxybutyl)- glycolohydroxamic acid bis-phosphate, a competitive inhibitor
Class: lyase/lyase inhibitor
Keywords: FBP aldolase, Class II, inhibitor, LYASE, LYASE-LYASE INHIBITOR complex
Deposited on 2010-05-31, released 2010-11-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2010-12-08, with a file datestamp of 2010-12-03.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.169
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fructose-bisphosphate aldolase
    Species: Helicobacter pylori [TaxId:290847]
    Gene: ALF_HELPY
    Database cross-references and differences (RAF-indexed):
    • Uniprot D0IR47 (0-306)
      • conflict (217)
    Domains in SCOPe 2.07: d3n9sa_
  • Chain 'B':
    Compound: Fructose-bisphosphate aldolase
    Species: Helicobacter pylori [TaxId:290847]
    Gene: ALF_HELPY
    Database cross-references and differences (RAF-indexed):
    • Uniprot D0IR47 (0-306)
      • conflict (217)
    Domains in SCOPe 2.07: d3n9sb_
  • Heterogens: TD4, ZN, CA, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3n9sA (A:)
mlvkgneillkahkegygvgafnfvnfemlnaifeagneensplfiqasegaikymgidm
avgmvkimceryphipvalhldhgttfescekavkagftsvmidashhafeenleltskv
vkmahnagvsveaelgrlmgiednisvdekdavlvnpkeaeqfvkesqvdylapaigtsh
gafkfkgepkldferlqevkrltniplvlhgasaipdnvrksyldaggdlkgskgvpfef
lqesvkgginkvntdtdlriafiaevrkvanedksqfdlrkffspaqlalknvvkermkl
lgsanki

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3n9sB (B:)
mlvkgneillkahkegygvgafnfvnfemlnaifeagneensplfiqasegaikymgidm
avgmvkimceryphipvalhldhgttfescekavkagftsvmidashhafeenleltskv
vkmahnagvsveaelgrlmgiednisvdekdavlvnpkeaeqfvkesqvdylapaigtsh
gafkfkgepkldferlqevkrltniplvlhgasaipdnvrksyldaggdlkgskgvpfef
lqesvkgginkvntdtdlriafiaevrkvanedksqfdlrkffspaqlalknvvkermkl
lgsanki

    Sequence, based on observed residues (ATOM records): (download) 
    >3n9sB (B:)
mlvkgneillkahkegygvgafnfvnfemlnaifeagneensplfiqasegaikymgidm
avgmvkimceryphipvalhldhgttfescekavkagftsvmidashhafeenleltskv
vkmahnagvsveaelgrlmavlvnpkeaeqfvkesqvdylapaigtshgafkfkgepkld
ferlqevkrltniplvlhgasaipdnvrksyldaggdlkgskgvpfeflqesvkgginkv
ntdtdlriafiaevrkvanedksqfdlrkffspaqlalknvvkermkllgsanki