SCOPe 2.04: Structural Classification of Proteins

PDB entry 3n59

View 3n59 on RCSB PDB site
Description: Type II dehydroquinase from Mycobacterium Tuberculosis complexed with 3-dehydroshikimate
Class: lyase
Keywords: DEHYDRATASE, SHIKIMATE PATHWAY, LYASE, AROMATIC AMINO ACID BIOSYNTHESIS, tuberculosis, drug target, 3-dehydroshikimate, Structural Genomics, TB Structural Genomics Consortium, TBSGC
Deposited on 2010-05-24, released 2010-07-21
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-06-08, with a file datestamp of 2011-06-03.
Experiment type: XRAY
Resolution: 2.52 Å
R-factor: 0.2
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59a_
Chain 'B':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59b_
Chain 'C':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59c_
Chain 'D':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59d_
Chain 'E':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59e_
Chain 'F':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59f_
Chain 'G':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59g_
Chain 'H':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59h_
Chain 'I':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59i_
Chain 'J':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59j_
Chain 'K':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59k_
Chain 'L':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59l_
Chain 'M':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6 (25-End)
  - expression tag (18-24)
Domains in SCOPe 2.04: d3n59m_
Chain 'N':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59n_
Chain 'O':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59o_
Chain 'P':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59p_
Chain 'Q':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59q_
Chain 'R':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59r_
Chain 'S':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59s_
Chain 'T':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59t_
Chain 'U':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59u_
Chain 'V':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59v_
Chain 'W':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59w_
Chain 'X':
Compound: 3-dehydroquinate dehydratase
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: aroD, aroQ, MT2612, MTCY159.19, Rv2537c
Database cross-references and differences (RAF-indexed):
- Uniprot P0A4Z6
Domains in SCOPe 2.04: d3n59x_
Heterogens: CL, 3DS, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>3n59A (A:)
mgsshhhhhhssglqgtenlyfqshmselivnvingpnlgrlgrrepavyggtthdelva
liereaaelglkavvrqsdseaqlldwihqaadaaepvilnagglthtsvalrdacaels
aplievhisnvhareefrrhsylspiatgvivglgiqgyllalrylaehvgt