PDB entry 3m1n

View 3m1n on RCSB PDB site
Description: Crystal structure of Human Sonic Hedgehog N-terminal domain
Class: signaling protein
Keywords: Hedgehog proteins, signaling, zinc ions, sulfate ions, autocatalytic cleavage, cell membrane, developmental protein, glycoprotein, holoprosencephaly, hydrolase, lipoprotein, membrane, microphthalmia, palmitate, protease, secreted, SIGNALING PROTEIN
Deposited on 2010-03-05, released 2010-03-16
The last revision prior to the SCOPe 2.03 freeze date was dated 2010-03-16, with a file datestamp of 2010-03-12.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.206
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Sonic hedgehog protein
    Species: Homo sapiens [TaxId:9606]
    Gene: SHH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3m1na_
  • Chain 'B':
    Compound: Sonic hedgehog protein
    Species: Homo sapiens [TaxId:9606]
    Gene: SHH
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q15465 (0-End)
      • engineered (0-1)
    Domains in SCOPe 2.03: d3m1nb_
  • Heterogens: ZN, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3m1nA (A:)
iigpgrgfgkrrhpkkltplaykqfipnvaektlgasgryegkisrnserfkeltpnynp
diifkdeentgadrlmtqrckdklnalaisvmnqwpgvklrvtegwdedghhseeslhye
gravdittsdrdrskygmlarlaveagfdwvyyeskahihcsvkaensvaaksgg

    Sequence, based on observed residues (ATOM records): (download) 
    >3m1nA (A:)
gpgrgfgkrrhpkkltplaykqfipnvaektlgasgryegkisrnserfkeltpnynpdi
ifkdeentgadrlmtqrckdklnalaisvmnqwpgvklrvtegwdedghhseeslhyegr
avdittsdrdrskygmlarlaveagfdwvyyeskahihcsvkae

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3m1nB (B:)
iigpgrgfgkrrhpkkltplaykqfipnvaektlgasgryegkisrnserfkeltpnynp
diifkdeentgadrlmtqrckdklnalaisvmnqwpgvklrvtegwdedghhseeslhye
gravdittsdrdrskygmlarlaveagfdwvyyeskahihcsvkaensvaaksgg

    Sequence, based on observed residues (ATOM records): (download) 
    >3m1nB (B:)
iigpgrgfgkrrhpkkltplaykqfipnvaektlgasgryegkisrnserfkeltpnynp
diifkdeentgadrlmtqrckdklnalaisvmnqwpgvklrvtegwdedghhseeslhye
gravdittsdrdrskygmlarlaveagfdwvyyeskahihcsvkaens