PDB entry 3kz0

View 3kz0 on RCSB PDB site
Description: MCL-1 complex with MCL-1-specific selected peptide
Class: apoptosis
Keywords: bcl-2, bh3, Mitochondrion, apoptosis, anti-apoptotic
Deposited on 2009-12-07, released 2010-05-05
The last revision prior to the SCOPe 2.04 freeze date was dated 2010-05-19, with a file datestamp of 2010-05-14.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.224
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL2L3, MCL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3kz0a_
  • Chain 'B':
    Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL2L3, MCL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3kz0b_
  • Chain 'C':
    Compound: Mcl-1 specific peptide MB7
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3KZ0 (0-22)
  • Chain 'D':
    Compound: Mcl-1 specific peptide MB7
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3KZ0 (0-22)
  • Heterogens: ZN, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3kz0A (A:)
gsdelyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafq
gmlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciep
laesitdvlvrtkrdwlvkqrgwdgfveffhvedlegg

    Sequence, based on observed residues (ATOM records): (download) 
    >3kz0A (A:)
delyrqsleiisrylreqatgakdgatsrkaletlrrvgdgvqrnhetafqgmlrkldik
neddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqescieplaesitdvl
vrtkrdwlvkqrgwdgfveffhv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3kz0B (B:)
gsdelyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafq
gmlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciep
laesitdvlvrtkrdwlvkqrgwdgfveffhvedlegg

    Sequence, based on observed residues (ATOM records): (download) 
    >3kz0B (B:)
delyrqsleiisrylreqatgakdrsgatsrkaletlrrvgdgvqrnhetafqgmlrkld
ikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqescieplaesitd
vlvrtkrdwlvkqrgwdgfveffhv

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.