PDB entry 3koa

View 3koa on RCSB PDB site
Description: M296I mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA and GTP
Class: Transferase/RNA
Keywords: RNA dependent RNA polymerase, ribavirin, 3D polymerase, foot-and-mouth disease virus, Transferase-RNA complex
Deposited on 2009-11-13, released 2010-07-07
The last revision prior to the SCOPe 2.04 freeze date was dated 2010-07-07, with a file datestamp of 2010-07-02.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.226
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3D polymerase
    Species: Foot-and-mouth disease virus - type C [TaxId:12116]
    Gene: 3D
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9QCE3 (0-469)
      • engineered mutation (295)
      • expression tag (470-475)
    Domains in SCOPe 2.04: d3koaa_
  • Chain 'B':
    Compound: RNA (5'-r(p*ap*up*gp*gp*gp*c)-3')
  • Chain 'C':
    Compound: RNA (5'-r(p*cp*cp*cp*g)-3')
  • Heterogens: MG, DPO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3koaA (A:)
glivdtrdveervhvmrktklaptvahgvfnpefgpaalsnkdprlnegvvldevifskh
kgdtkmsaedkalfrrcaadyasrlhsvlgtanaplsiyeaikgvdgldamepdtapglp
walqgkrrgalidfengtvgpeveaalklmekreykfacqtflkdeirpmekvragktri
vdvlpvehilytrmmigrfcaqmhsnngpqigsavgcnpdvdwqrfgthfaqyrnvwdvd
ysafdanhcsdamnimfeevfrtefgfhpnaewilktlvntehayenkritveggipsgc
satsiintilnniyvlyalrrhyegveldtytmisygddivvasdydldfealkphfksl
gqtitpadksdkgfvlghsitdvtflkrhfhmdygtgfykpvmasktleailsfarrgti
qeklisvaglavhsgpdeyrrlfepfqglfeipsyrslylrwvnavcgdaaalehh

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.