PDB entry 3kjr

View 3kjr on RCSB PDB site
Description: Crystal structure of dihydrofolate reductase/thymidylate synthase from Babesia bovis determined using SlipChip based microfluidics
Class: transferase
Keywords: Microfluidics, SlipChip,Structural Genomics, PSI-2, Protein Structure Initiative, Accelerated Technologies Center for Gene to 3D Structure, ATCG3D, Seattle Structural Genomics Center for Infectious Disease, Methyltransferase, Transferase, SSGCID
Deposited on 2009-11-03, released 2009-11-17
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.17
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dihydrofolate reductase/thymidylate synthase
    Species: Babesia bovis T2Bo [TaxId:484906]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3kjra1, d3kjra2
  • Chain 'B':
    Compound: Dihydrofolate reductase/thymidylate synthase
    Species: Babesia bovis T2Bo [TaxId:484906]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3kjrb1, d3kjrb2
  • Heterogens: NAP, NHE, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3kjrA (A:)
msnsyegcgdltifvavalnkvighknqipwphithdfrflrngttyippevlsknpdiq
nvvifgrktyesipkaslplknrinvilsrtvkevpgclvyedlstairdlranvphnki
filggsflykevldnglcdkiyltrlnkeypgdtyfpdipdtfeitaisptfstdfvsyd
fviyerkdcktvfpdppfdqllmtgtdisvpkpkyvacpgvrirnheefqyldiladvls
hgvlkpnrtgtdayskfgyqmrfdlsrsfpllttkkvalrsiieellwfikgstngndll
aknvriwelngrrdfldkngftdreehdlgpiygfqwrhfgaeyldmhadytgkgidqla
eiinriktnpndrrlivcswnvsdlkkmalppchcffqfyvsdnklscmmhqrscdlglg
vpfniasysiltamvaqvcglglgefvhnladahiyvdhvdavttqiariphpfprlrln
pdirniedftiddivvedyvshppipmamsa

    Sequence, based on observed residues (ATOM records): (download) 
    >3kjrA (A:)
yegcgdltifvavalnkvighknqipwphithdfrflrngttyippevlsknpdiqnvvi
fgrktyesipkaslplknrinvilsrtvkevpgclvyedlstairdlranvphnkifilg
gsflykevldnglcdkiyltrlnkeypgdtyfpdipdtfeitaisptfstdfvsydfviy
erkpfdqllmtgtdisvpkpkyvacpgvrirnheefqyldiladvlshgvlkpnrtgtda
yskfgyqmrfdlsrsfpllttkkvalrsiieellwfikgstngndllaknvriwelngrr
dfldkngftdreehdlgpiygfqwrhfgaeyldmhadytgkgidqlaeiinriktnpndr
rlivcswnvsdlkkmalppchcffqfyvsdnklscmmhqrscdlglgvpfniasysilta
mvaqvcglglgefvhnladahiyvdhvdavttqiariphpfprlrlnpdirniedftidd
ivvedyvshppipmamsa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3kjrB (B:)
msnsyegcgdltifvavalnkvighknqipwphithdfrflrngttyippevlsknpdiq
nvvifgrktyesipkaslplknrinvilsrtvkevpgclvyedlstairdlranvphnki
filggsflykevldnglcdkiyltrlnkeypgdtyfpdipdtfeitaisptfstdfvsyd
fviyerkdcktvfpdppfdqllmtgtdisvpkpkyvacpgvrirnheefqyldiladvls
hgvlkpnrtgtdayskfgyqmrfdlsrsfpllttkkvalrsiieellwfikgstngndll
aknvriwelngrrdfldkngftdreehdlgpiygfqwrhfgaeyldmhadytgkgidqla
eiinriktnpndrrlivcswnvsdlkkmalppchcffqfyvsdnklscmmhqrscdlglg
vpfniasysiltamvaqvcglglgefvhnladahiyvdhvdavttqiariphpfprlrln
pdirniedftiddivvedyvshppipmamsa

    Sequence, based on observed residues (ATOM records): (download) 
    >3kjrB (B:)
yegcgdltifvavalnkvighknqipwphithdfrflrngttyippevlsknpdiqnvvi
fgrktyesipkaslplknrinvilsrtvkevpgclvyedlstairdlranvphnkifilg
gsflykevldnglcdkiyltrlnkeypgdtyfpdipdtfeitaisptfstdfvsydfviy
erkpfdqllmtgtdisvpkpkyvacpgvrirnheefqyldiladvlshgvlkpnrtgtda
yskfgyqmrfdlsrsfpllttkkvalrsiieellwfikgstngndllaknvriwelngrr
dfldkngftdreehdlgpiygfqwrhfgaeyldmhadytgkgidqlaeiinriktnpndr
rlivcswnvsdlkkmalppchcffqfyvsdnklscmmhqrscdlglgvpfniasysilta
mvaqvcglglgefvhnladahiyvdhvdavttqiariphpfprlrlnpdirniedftidd
ivvedyvshppipma