PDB entry 3kgc

View 3kgc on RCSB PDB site
Description: Isolated ligand binding domain dimer of GluA2 ionotropic glutamate receptor in complex with glutamate, LY 404187 and ZK 200775
Class: Membrane protein, transport protein
Keywords: glutamate receptor, S1S2, agonist, antagonist, modulator, soluble domain, ligand binding, Ion transport, Ionic channel, Postsynaptic cell membrane, Receptor, Synapse, membrane protein, glutamate, LY 404187, ZK 200775, transport protein
Deposited on 2009-10-28, released 2009-12-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-08-16, with a file datestamp of 2017-08-11.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Glur2, Gria2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (120-End)
      • linker (117-119)
      • engineered (241)
    Domains in SCOPe 2.07: d3kgca_
  • Chain 'B':
    Compound: Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Glur2, Gria2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (120-261)
      • linker (117-119)
      • engineered (241)
    Domains in SCOPe 2.07: d3kgcb_
  • Heterogens: GLU, SO4, LY7, ZK1, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3kgcA (A:)
ganktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgk
ygardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtp
iesaedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvar
vrkskgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlk
lseqglldklknkwwydkgecgs

    Sequence, based on observed residues (ATOM records): (download) 
    >3kgcA (A:)
tvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkygar
dadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpiesa
edlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrks
kgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlklseq
glldklknkwwydkgec

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3kgcB (B:)
ganktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgk
ygardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtp
iesaedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvar
vrkskgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlk
lseqglldklknkwwydkgecgs

    Sequence, based on observed residues (ATOM records): (download) 
    >3kgcB (B:)
ktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyga
rdadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpies
aedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrk
skgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlklse
qglldklknkwwydkgecg