PDB entry 3i6k

View 3i6k on RCSB PDB site
Description: Newly identified epitope from SARS-CoV membrane protein complexed with HLA-A*0201
Class: Immune System
Keywords: HLA-A2, SARS-CoV, Membrane glycoprotein, Disulfide bond, Glycoprotein, Host-virus interaction, Immune response, Membrane, MHC I, Phosphoprotein, Transmembrane, Disease mutation, Glycation, Immunoglobulin domain, Pyrrolidone carboxylic acid, Secreted, Envelope protein, Golgi apparatus, Viral matrix protein, Virion, Immune System
Deposited on 2009-07-07, released 2010-06-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2010-11-03, with a file datestamp of 2010-10-29.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.2
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: HLA class I histocompatibility antigen, A-2 alpha chain
  Species: Homo sapiens [TaxId:9606]
  Gene: HLA-A, HLA-A*0201 allele, HLAA, Homo sapiens MHC class I antigen (HLA-A)
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01892 (0-274)
• Chain 'B':
  Compound: Beta-2-microglobulin
  Species: Homo sapiens [TaxId:9606]
  Gene: B2M, beta-2-microglobulin, CDABP0092, HDCMA22P
  Database cross-references and differences (RAF-indexed):
  • Uniprot P61769 (1-99)
    • initiating methionine (0)
  Domains in SCOPe 2.07: d3i6kb1, d3i6kb2
• Chain 'C':
  Compound: Membrane glycoprotein peptide
  Species: SARS coronavirus TJF, synthetic [TaxId:284672]
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q692E0 (0-9)
• Chain 'E':
  Compound: HLA class I histocompatibility antigen, A-2 alpha chain
  Species: Homo sapiens [TaxId:9606]
  Gene: HLA-A, HLA-A*0201 allele, HLAA, Homo sapiens MHC class I antigen (HLA-A)
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01892 (0-274)
• Chain 'F':
  Compound: Beta-2-microglobulin
  Species: Homo sapiens [TaxId:9606]
  Gene: B2M, beta-2-microglobulin, CDABP0092, HDCMA22P
  Database cross-references and differences (RAF-indexed):
  • Uniprot P61769 (1-99)
    • initiating methionine (0)
  Domains in SCOPe 2.07: d3i6kf1, d3i6kf2
• Chain 'G':
  Compound: Membrane glycoprotein peptide
  Species: SARS coronavirus TJF, synthetic [TaxId:284672]
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q692E0 (0-9)
• Heterogens: HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3i6kB (B:)
  miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
  wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'E':
  No sequence available.
  
  
• Chain 'F':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3i6kF (F:)
  miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
  wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  
• Chain 'G':
  No sequence available.