PDB entry 3hy9

View 3hy9 on RCSB PDB site
Description: Crystal Structure of the Catalytic Domain of ADAMTS-5 in Complex with an Amino-2-indanol compound
Class: hydrolase
Keywords: alpha/beta structure, central five stranded beta-sheet, HYDROLASE
Deposited on 2009-06-22, released 2009-07-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2.02 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Catalytic Domain of ADAMTS-5
    Species: Homo sapiens [TaxId:9606]
    Gene: ADAMTS-5
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UNA0 (Start-220)
      • engineered (22)
    Domains in SCOPe 2.07: d3hy9a_
  • Chain 'B':
    Compound: Catalytic Domain of ADAMTS-5
    Species: Homo sapiens [TaxId:9606]
    Gene: ADAMTS-5
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UNA0 (2-220)
      • expression tag (1)
      • engineered (22)
    Domains in SCOPe 2.07: d3hy9b1, d3hy9b2
  • Heterogens: ZN, CA, 098, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3hy9A (A:)
masisrarqvelllvadasmarkygrglqhylltlasianrlyshasienhirlavvkvv
vlgdkdkslevsknaattlknfckwqhqhnqlgddheehydaailftredlcghhscdtl
gmadvgticsperscavieddglhaaftvaheighllglshddskfceetfgstedkrlm
ssiltsidaskpwskctsatiteflddghgnclldlprkqi

    Sequence, based on observed residues (ATOM records): (download) 
    >3hy9A (A:)
srarqvelllvadasmarkygrglqhylltlasianrlyshasienhirlavvkvvvlgd
kdkslevsknaattlknfckwqhqhnqlgddheehydaailftredlcghhscdtlgmad
vgticsperscavieddglhaaftvaheighllglshddskfceetfgstedkrlmssil
tsidaskpwskctsatiteflddghgnclldlprkqi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3hy9B (B:)
masisrarqvelllvadasmarkygrglqhylltlasianrlyshasienhirlavvkvv
vlgdkdkslevsknaattlknfckwqhqhnqlgddheehydaailftredlcghhscdtl
gmadvgticsperscavieddglhaaftvaheighllglshddskfceetfgstedkrlm
ssiltsidaskpwskctsatiteflddghgnclldlprkqi

    Sequence, based on observed residues (ATOM records): (download) 
    >3hy9B (B:)
asisrarqvelllvadasmarkygrglqhylltlasianrlyshasienhirlavvkvvv
lgdkdkslevsknaattlknfckwqhqhnqlgddheehydaailftredlcghhscdtlg
madvgticsperscavieddglhaaftvaheighllglshddskfceetfgstedkrlms
siltsidaskpwskctsatiteflddghgnclldlprkqi