PDB entry 3fhy

View 3fhy on RCSB PDB site
Description: Crystal structure of D235N mutant of human pyridoxal kinase
Class: transferase
Keywords: beta sheet with alpha helix, ATP complex, metal ion, transferase, Acetylation, Alternative splicing, ATP-binding, Cytoplasm, Kinase, Metal-binding, Nucleotide-binding, Zinc
Deposited on 2008-12-10, released 2008-12-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-04-21, with a file datestamp of 2009-04-17.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.214
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pyridoxal kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: C21orf124, C21orf97, PDXK, PKH, PNK
    Database cross-references and differences (RAF-indexed):
    • Uniprot O00764 (Start-311)
      • engineered (234)
    Domains in SCOPe 2.07: d3fhya_
  • Chain 'B':
    Compound: Pyridoxal kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: C21orf124, C21orf97, PDXK, PKH, PNK
    Database cross-references and differences (RAF-indexed):
    • Uniprot O00764 (Start-311)
      • engineered (234)
    Domains in SCOPe 2.07: d3fhyb_
  • Heterogens: MG, NA, ATP, SO4, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3fhyA (A:)
meeecrvlsiqshvirgyvgnraatfplqvlgfeidavnsvqfsnhtgyahwkgqvlnsd
elqelyeglrlnnmnkydyvltgytrdksflamvvdivqelkqqnprlvyvcdpvlgdkw
dgegsmyvpedllpvykekvvpladiitpnqfeaellsgrkihsqeealrvmdmlhsmgp
dtvvitssdlpspqgsnylivlgsqrrrnpagsvvmerirmdirkvdavfvgtgnlfaam
llawthkhpnnlkvacektvstlhhvlqrtiqcakaqagegvrpspmqlelrmvqskrdi
edpeivvqatvl

    Sequence, based on observed residues (ATOM records): (download) 
    >3fhyA (A:)
ecrvlsiqshvirgyvgnraatfplqvlgfeidavnsvqfsnhtgyahwkgqvlnsdelq
elyeglrlnnmnkydyvltgytrdksflamvvdivqelkqqnprlvyvcdpvlgdkwdge
gsmyvpedllpvykekvvpladiitpnqfeaellsgrkihsqeealrvmdmlhsmgpdtv
vitssdlpspqgsnylivlgsqrrrnpvvmerirmdirkvdavfvgtgnlfaamllawth
khpnnlkvacektvstlhhvlqrtiqcakaqagegvrpspmqlelrmvqskrdiedpeiv
vqatvl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3fhyB (B:)
meeecrvlsiqshvirgyvgnraatfplqvlgfeidavnsvqfsnhtgyahwkgqvlnsd
elqelyeglrlnnmnkydyvltgytrdksflamvvdivqelkqqnprlvyvcdpvlgdkw
dgegsmyvpedllpvykekvvpladiitpnqfeaellsgrkihsqeealrvmdmlhsmgp
dtvvitssdlpspqgsnylivlgsqrrrnpagsvvmerirmdirkvdavfvgtgnlfaam
llawthkhpnnlkvacektvstlhhvlqrtiqcakaqagegvrpspmqlelrmvqskrdi
edpeivvqatvl

    Sequence, based on observed residues (ATOM records): (download) 
    >3fhyB (B:)
ecrvlsiqshvirgyvgnraatfplqvlgfeidavnsvqfsnhtgyahwkgqvlnsdelq
elyeglrlnnmnkydyvltgytrdksflamvvdivqelkqqnprlvyvcdpvlgdkwdge
gsmyvpedllpvykekvvpladiitpnqfeaellsgrkihsqeealrvmdmlhsmgpdtv
vitssdlpspqgsnylivlgsqrrrnpagsvvmerirmdirkvdavfvgtgnlfaamlla
wthkhpnnlkvacektvstlhhvlqrtiqcakaqagrpspmqlelrmvqskrdiedpeiv
vqatvl