PDB entry 3bm8

View 3bm8 on RCSB PDB site
Description: crystal structure of YopH mutant D356A complexed with irreversible inhibitor PVSN
Class: hydrolase
Keywords: co-valent binding, PVSN, binding selectivity, binding affinity, Hydrolase, Membrane, Outer membrane, Plasmid, Protein phosphatase, Secreted, Virulence
Deposited on 2007-12-12, released 2008-06-17
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.179
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein phosphatase yopH
    Species: Yersinia enterocolitica
    Gene: yopH, yop51
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15273 (Start-304)
      • engineered (71)
      • engineered (192)
    Domains in SCOPe 2.03: d3bm8a_
  • Heterogens: PSY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3bm8A (A:)
rerphtsghhgagearatapstvspygpearaelssrlttlrntlapatndprylqacgg
eklnrfrdiqcrrqtavradlnanyiqvgntrtiacqyplqsqleshfrmlaenrtpvla
vlassseianqrfgmpdyfrqsgtygsitveskmtqqvglgdgimadmytltireagqkt
isvpvvhvgnwpaqtavssevtkalaslvdqtaetkrnmyeskgssavaddsklrpvihc
ragvgrtaqligamcmndsrnsqlsvedmvsqmrvqrngimvqkdeqldvliklaegqgr
pllns

    Sequence, based on observed residues (ATOM records): (download) 
    >3bm8A (A:)
spygpearaelssrlttlrntlapatndprylqacggeklnrfrdiqcrrqtavradlna
nyiqvgntrtiacqyplqsqleshfrmlaenrtpvlavlassseianqrfgmpdyfrqsg
tygsitveskmtqqvglgdgimadmytltireagqktisvpvvhvgnwpaqtavssevtk
alaslvdqtaetkrnmyeskgssavaddsklrpvihcragvgrtaqligamcmndsrnsq
lsvedmvsqmrvqrngimvqkdeqldvliklaegqgrpllns