PDB entry 3bc5
View 3bc5 on RCSB PDB site
Description: X-ray crystal structure of human ppar gamma with 2-(5-(3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzyl)-2-phenyl-2h-1,2,3-triazol-4-yl)acetic acid
Class: transcription
Keywords: ligand-binding domain, nuclear hormone receptor, transcription factor, Activator, Alternative splicing, Diabetes mellitus, Disease mutation, DNA-binding, Metal-binding, Nucleus, Obesity, Phosphorylation, Polymorphism, Transcription regulation, Zinc, Zinc-finger
Deposited on
2007-11-12, released
2008-11-18
The last revision prior to the SCOPe 2.04 freeze date was dated
2009-03-31, with a file datestamp of
2009-03-27.
Experiment type: XRAY
Resolution: 2.27 Å
R-factor: 0.212
AEROSPACI score: 0.35
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Peroxisome proliferator-activated receptor gamma
Species: Homo sapiens [TaxId:9606]
Gene: PPARG, NR1C3
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d3bc5a_ - Heterogens: ZAA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3bc5A (A:)
mgsshhhhhhssglvprgshmqlnpesadlralakhlydsyiksfpltkakarailtgkt
tdkspfviydmnslmmgedkikfkhitplqeqskevairifqgcqfrsveavqeiteyak
sipgfvnldlndqvtllkygvheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfg
dfmepkfefavkfnalelddsdlaifiaviilsgdrpgllnvkpiediqdnllqalelql
klnhpessqlfakllqkmtdlrqivtehvqllqvikktetdmslhpllqeiykdly
Sequence, based on observed residues (ATOM records): (download)
>3bc5A (A:)
mqlnpesadlralakhlydsyiksfpltkakarailtgktspfviydmnslmmgedkikf
khkevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlas
lmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiavii
lsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvql
lqvikktemslhpllqeiykdly