PDB entry 3a7n

View 3a7n on RCSB PDB site
Description: Crystal structure of uracil-DNA glycosylase from Mycobacterium tuberculosis
Class: hydrolase
Keywords: Ung-Ugi interactions, Ung-DNA complex, citrate as protein ligand, ligand binding, inhibitor design, DNA damage, DNA repair, Glycosidase, Hydrolase
Deposited on 2009-09-29, released 2010-08-11
The last revision prior to the SCOPe 2.04 freeze date was dated 2010-08-18, with a file datestamp of 2010-08-13.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.182
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: uracil-DNA glycosylase
    Species: Mycobacterium tuberculosis H37Rv [TaxId:83332]
    Gene: ung, Rv2976c
    Database cross-references and differences (RAF-indexed):
    • Uniprot P67071 (11-237)
      • expression tag (5-10)
    Domains in SCOPe 2.04: d3a7na_
  • Heterogens: FLC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3a7nA (A:)
mhhhhhhgmasmtarplselvergwaaalepvadqvahmgqflraeiaagrrylpagsnv
lraftfpfdnvrvlivgqdpyptpghavglsfsvapdvrpwprslanifdeytadlgypl
psngdltpwaqrgvlllnrvltvrpsnpashrgkgweavtecairalaaraaplvailwg
rdastlkpmlaagncvaiesphpsplsasrgffgsrpfsranellvgmgaepidwrlp

    Sequence, based on observed residues (ATOM records): (download) 
    >3a7nA (A:)
hhgmasmtarplselvergwaaalepvadqvahmgqflraeiaagrrylpagsnvlraft
fpfdnvrvlivgqdpyptpghavglsfsvapdvrpwprslanifdeytadlgyplpsngd
ltpwaqrgvlllnrvltvrpsnpashrgkgweavtecairalaaraaplvailwgrdast
lkpmlaagncvaiesphpsplsasrgffgsrpfsranellvgmgaepidwrlp