PDB entry 2x30

View 2x30 on RCSB PDB site
Description: crystal structure of the r139n mutant of a bifunctional enzyme pria
Class: isomerase
Keywords: aromatic amino acid biosynthesis, tryptophan biosynthesis, conformational diversity, dual-substrate specificity, histidine biosynthesis, isomerase, loops motion, hisa, trpf
Deposited on 2010-01-20, released 2010-02-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-06-02.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.21816
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phosphoribosyl isomerase a
    Species: STREPTOMYCES COELICOLOR [TaxId:1902]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16250 (0-239)
      • engineered mutation (138)
    Domains in SCOPe 2.07: d2x30a_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2x30A (A:)
msklellpavdvrdgqavrlvhgesgtetsygspleaalawqrsgaewlhlvdldaafgt
gdnraliaevaqamdikvelsggirdddtlaaalatgctrvnlgtaaletpewvakviae
hgdkiavgldvrgttlrgngwtrdggdlyetldrlnkegcaryvvtdiakdgtlqgpnle
llknvcaatdrpvvasggvsslddlraiaglvpagvegaivgkalyakaftleealeats

    Sequence, based on observed residues (ATOM records): (download) 
    >2x30A (A:)
msklellpavdvrdgqavrlvhgesgtetsygspleaalawqrsgaewlhlvdldaafgt
gdnraliaevaqamdikvelsggirdddtlaaalatgctrvnlgtaaletpewvakviae
hgdkiavgldvrgttlrgngwtrdggdlyetldrlnkegcaryvvtdiapnlellknvca
atdrpvvasggvsslddlraiaglvpagvegaivgkalyakaftleealeats