PDB entry 2wfq
View 2wfq on RCSB PDB site
Description: crystal structure of the n-terminal signalling domain of human dhh without calcium
Class: signaling protein
Keywords: lipoprotein, development, cell membrane, autocatalytic cleavage, signaling protein, disease mutation, hedgehog signalling, protease, membrane, secreted, palmitate, hydrolase, signal transduction, developmental protein
Deposited on
2009-04-14, released
2009-06-30
The last revision prior to the SCOPe 2.04 freeze date was dated
2011-07-13, with a file datestamp of
2011-06-02.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.18918
AEROSPACI score: 0.49
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: desert hedgehog protein n-product
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot O43323 (Start-155)
- PDB 2WFQ (156-164)
Domains in SCOPe 2.04: d2wfqa_ - Heterogens: ZN, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2wfqA (A:)
qlvpllykqfvpgvpertlgasgpaegrvargserfrdlvpnynpdiifkdeensgadrl
mterckervnalaiavmnmwpgvrlrvtegwdedghhaqdslhyegraldittsdrdrnk
ygllarlaveagfdwvyyesrnhvhvsvkadnslavklehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>2wfqA (A:)
lvpllykqfvpgvpertlgasgpaegrvargserfrdlvpnynpdiifkdeensgadrlm
terckervnalaiavmnmwpgvrlrvtegwdedghhaqdslhyegraldittsdrdrnky
gllarlaveagfdwvyyesrnhvhvsvkadnslavklehhhhhh