SCOPe 2.07: Structural Classification of Proteins

PDB entry 2vo5

View 2vo5 on RCSB PDB site
Description: structural and biochemical evidence for a boat-like transition state in beta-mannosidases
Class: hydrolase
Keywords: glycoside, hydrolase, mannosidase, transition state mimic, linear free energy relationship
Deposited on 2008-02-08, released 2008-04-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.173
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: beta-mannosidase
Species: BACTEROIDES THETAIOTAOMICRON [TaxId:226186]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8AAK6 (Start-838)
- PDB 2VO5
Domains in SCOPe 2.07: d2vo5a1, d2vo5a2, d2vo5a3, d2vo5a4, d2vo5a5
Chain 'B':
Compound: beta-mannosidase
Species: BACTEROIDES THETAIOTAOMICRON [TaxId:226186]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8AAK6 (Start-838)
- PDB 2VO5 (839-End)
Domains in SCOPe 2.07: d2vo5b1, d2vo5b2, d2vo5b3, d2vo5b4, d2vo5b5, d2vo5b6
Heterogens: VBZ, EDO, BR, CL, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2vo5A (A:)
qgndtsevmlldtgwefsqsgtekwmpatvpgtvhqdlishellpnpfygmnekkiqwve
nedweyrtsfivseeqlnrdgiqlifegldtyadvylngslllkadnmfvgytlpvksvl
rkgenhlyiyfhspirqtlpqyasngfnypadndhhekhlsvfsrkapysygwdwgirmv
tsgvwrpvtlrfydiatisdyyvrqlsltdenarlsnelivnqivpqkipaevrvnvsln
gttvtevkqqvtlqpginhitlpaevtnpvrwmpngwgtptlydfsaqiacgdrivaeqs
hriglrtirvvnekdkdgesfyfevngipmfakganyipqdallpnvtteryqtlfrdmk
eanmnmvriwgggtyennlfydladengilvwqdfmfactpypsdptflkrveaeavyni
rrlrnhaslamwcgnneilealkywgfekkftpevyqglmhgydklfrellpstvkefds
drfyvhsspylanwgrpeswgtgdshnwgvwygkkpfesldtdlprfmsefgfqsfpemk
tiaafaapedyqiesevmnahqkssignslirtymerdyiipesfedfvyvglvlqgqgm
rhgleahrrnrpycmgtlywqlndswpvvswssidyygnwkalhyqakrafapvlinpiq
qndslsvylisdrldtmeqmtlemkvvdfdgktlgkkiqvhslevpantskcvyrakldg
wltpedcrrsflklilkdksghqvaesvhffrktkdlqlpptsvsyqmkqtdgkceltlf
ssmlakdifietplqgarysdnffdllpgerkkviitsprikkgeelpvnikhiretyke
hhhhhh

Sequence, based on observed residues (ATOM records): (download)

>2vo5A (A:)
ndtsevmlldtgwefsqsgtekwmpatvpgtvhqdlishellpnpfygmnekkiqwvene
dweyrtsfivseeqlnrdgiqlifegldtyadvylngslllkadnmfvgytlpvksvlrk
genhlyiyfhspirqtlpqyasngfnypadndhhekhlsvfsrkapysygwdwgirmvts
gvwrpvtlrfydiatisdyyvrqlsltdenarlsnelivnqivpqkipaevrvnvslngt
tvtevkqqvtlqpginhitlpaevtnpvrwmpngwgtptlydfsaqiacgdrivaeqshr
iglrtirvvnekdkdgesfyfevngipmfakganyipqdallpnvtteryqtlfrdmkea
nmnmvriwgggtyennlfydladengilvwqdfmfactpypsdptflkrveaeavynirr
lrnhaslamwcgnneilealkywgfekkftpevyqglmhgydklfrellpstvkefdsdr
fyvhsspylanwgrpeswgtgdshnwgvwygkkpfesldtdlprfmsefgfqsfpemkti
aafaapedyqiesevmnahqkssignslirtymerdyiipesfedfvyvglvlqgqgmrh
gleahrrnrpycmgtlywqlndswpvvswssidyygnwkalhyqakrafapvlinpiqqn
dslsvylisdrldtmeqmtlemkvvdfdgktlgkkiqvhslevpantskcvyrakldgwl
tpedcrrsflklilkdksghqvaesvhffrktkdlqlpptsvsyqmkqtdgkceltlfss
mlakdifietplqgarysdnffdllpgerkkviitspriklpvnikhiretyk

Chain 'B':
Sequence, based on SEQRES records: (download)

>2vo5B (B:)
qgndtsevmlldtgwefsqsgtekwmpatvpgtvhqdlishellpnpfygmnekkiqwve
nedweyrtsfivseeqlnrdgiqlifegldtyadvylngslllkadnmfvgytlpvksvl
rkgenhlyiyfhspirqtlpqyasngfnypadndhhekhlsvfsrkapysygwdwgirmv
tsgvwrpvtlrfydiatisdyyvrqlsltdenarlsnelivnqivpqkipaevrvnvsln
gttvtevkqqvtlqpginhitlpaevtnpvrwmpngwgtptlydfsaqiacgdrivaeqs
hriglrtirvvnekdkdgesfyfevngipmfakganyipqdallpnvtteryqtlfrdmk
eanmnmvriwgggtyennlfydladengilvwqdfmfactpypsdptflkrveaeavyni
rrlrnhaslamwcgnneilealkywgfekkftpevyqglmhgydklfrellpstvkefds
drfyvhsspylanwgrpeswgtgdshnwgvwygkkpfesldtdlprfmsefgfqsfpemk
tiaafaapedyqiesevmnahqkssignslirtymerdyiipesfedfvyvglvlqgqgm
rhgleahrrnrpycmgtlywqlndswpvvswssidyygnwkalhyqakrafapvlinpiq
qndslsvylisdrldtmeqmtlemkvvdfdgktlgkkiqvhslevpantskcvyrakldg
wltpedcrrsflklilkdksghqvaesvhffrktkdlqlpptsvsyqmkqtdgkceltlf
ssmlakdifietplqgarysdnffdllpgerkkviitsprikkgeelpvnikhiretyke
hhhhhh

Sequence, based on observed residues (ATOM records): (download)

>2vo5B (B:)
gndtsevmlldtgwefsqsgtekwmpatvpgtvhqdlishellpnpfygmnekkiqwven
edweyrtsfivseeqlnrdgiqlifegldtyadvylngslllkadnmfvgytlpvksvlr
kgenhlyiyfhspirqtlpqyasngfnypadndhhekhlsvfsrkapysygwdwgirmvt
sgvwrpvtlrfydiatisdyyvrqlsltdenarlsnelivnqivpqkipaevrvnvslng
ttvtevkqqvtlqpginhitlpaevtnpvrwmpngwgtptlydfsaqiacgdrivaeqsh
riglrtirvvnekdkdgesfyfevngipmfakganyipqdallpnvtteryqtlfrdmke
anmnmvriwgggtyennlfydladengilvwqdfmfactpypsdptflkrveaeavynir
rlrnhaslamwcgnneilealkywgfekkftpevyqglmhgydklfrellpstvkefdsd
rfyvhsspylanwgrpeswgtgdshnwgvwygkkpfesldtdlprfmsefgfqsfpemkt
iaafaapedyqiesevmnahqkssignslirtymerdyiipesfedfvyvglvlqgqgmr
hgleahrrnrpycmgtlywqlndswpvvswssidyygnwkalhyqakrafapvlinpiqq
ndslsvylisdrldtmeqmtlemkvvdfdgktlgkkiqvhslevpantskcvyrakldgw
ltpedcrrsflklilkdksghqvaesvhffrktkdlqlpptsvsyqmkqtdgkceltlfs
smlakdifietplqgarysdnffdllpgerkkviitsprikkgeelpvnikhiretykeh
h