PDB entry 2q70

View 2q70 on RCSB PDB site
Description: Estrogen receptor alpha ligand-binding domain complxed to a benzopyran ligand
Class: transcription
Keywords: transcription factor, estrogen receptor
Deposited on 2007-06-05, released 2007-08-07
The last revision prior to the SCOP 1.75 freeze date was dated 2007-10-30, with a file datestamp of 2007-10-26.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.26
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Estrogen receptor
    Species: HOMO SAPIENS
    Gene: ESR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03372
      • engineered (77)
      • engineered (113)
    Domains in SCOP 1.75: d2q70a1
  • Chain 'B':
    Compound: Estrogen receptor
    Species: HOMO SAPIENS
    Gene: ESR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03372
      • engineered (77)
      • engineered (113)
  • Heterogens: DC8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2q70A (A:)
nslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakr
vpgfvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmve
ifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkit
dtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvplydlllem
ldahrlha

    Sequence, based on observed residues (ATOM records): (download) 
    >2q70A (A:)
lalsltadqmvsalldaeppilyseydpseasmmglltnladrelvhminwakrvpgfvd
ltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifdmll
atssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtlihl
makagltlqqqhqrlaqlllilshirhmsnkgmehlysmvplydlllemldahrl

  • Chain 'B':
    No sequence available.