SCOP 1.75: Domain d2q70a1: 2q70 A:306-549

Lineage for d2q70a1 (2q70 A:306-549)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (33 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (29 PDB entries)
   Uniprot P03372 307-551

8. Domain d2q70a1: 2q70 A:306-549 [150072]
   automatically matched to d1qkta_
   complexed with dc8; mutant

Details for d2q70a1

PDB Entry: 2q70, 1.95 Å

PDB Description: estrogen receptor alpha ligand-binding domain complxed to a benzopyran ligand

PDB Compounds: (A:) Estrogen receptor

SCOP Domain Sequences for d2q70a1:

Sequence, based on SEQRES records:

>d2q70a1 a.123.1.1 (A:306-549) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvplydlllemld
ahrl

Sequence, based on observed residues (ATOM records):

>d2q70a1 a.123.1.1 (A:306-549) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydpseasmmglltnladrelvhminwakrvpgfvd
ltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifdmll
atssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtlihl
makagltlqqqhqrlaqlllilshirhmsnkgmehlysmvplydlllemldahrl

Timeline for d2q70a1:

• d2q70a1 is new in SCOP 1.75
  
• d2q70a1 is called d2q70a_ in SCOPe 2.01
  
• d2q70a1 appears in the current release, SCOPe 2.08, called d2q70a_